Transcription coordinates histone amounts and genome content
Accurate regulation of protein concentrations according to changes in cell volume that accompany growth and changes in biosynthetic capacity is an important component of cellular homeostasis. Here, using the model organism S. cerevisiae, the authors show how histone production is quantitatively coup...
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2021-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-24451-8 |
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doaj-5b228a49de404295a27fdb7a29d0d3e82021-07-11T11:42:21ZengNature Publishing GroupNature Communications2041-17232021-07-0112111710.1038/s41467-021-24451-8Transcription coordinates histone amounts and genome contentKora-Lee Claude0Daniela Bureik1Dimitra Chatzitheodoridou2Petia Adarska3Abhyudai Singh4Kurt M. Schmoller5Institute of Functional Epigenetics, Helmholtz Zentrum MünchenInstitute of Functional Epigenetics, Helmholtz Zentrum MünchenInstitute of Functional Epigenetics, Helmholtz Zentrum MünchenInstitute of Functional Epigenetics, Helmholtz Zentrum MünchenDepartment of Electrical & Computer Engineering, University of DelawareInstitute of Functional Epigenetics, Helmholtz Zentrum MünchenAccurate regulation of protein concentrations according to changes in cell volume that accompany growth and changes in biosynthetic capacity is an important component of cellular homeostasis. Here, using the model organism S. cerevisiae, the authors show how histone production is quantitatively coupled to genome content through the intrinsic properties of histone promoters.https://doi.org/10.1038/s41467-021-24451-8 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kora-Lee Claude Daniela Bureik Dimitra Chatzitheodoridou Petia Adarska Abhyudai Singh Kurt M. Schmoller |
spellingShingle |
Kora-Lee Claude Daniela Bureik Dimitra Chatzitheodoridou Petia Adarska Abhyudai Singh Kurt M. Schmoller Transcription coordinates histone amounts and genome content Nature Communications |
author_facet |
Kora-Lee Claude Daniela Bureik Dimitra Chatzitheodoridou Petia Adarska Abhyudai Singh Kurt M. Schmoller |
author_sort |
Kora-Lee Claude |
title |
Transcription coordinates histone amounts and genome content |
title_short |
Transcription coordinates histone amounts and genome content |
title_full |
Transcription coordinates histone amounts and genome content |
title_fullStr |
Transcription coordinates histone amounts and genome content |
title_full_unstemmed |
Transcription coordinates histone amounts and genome content |
title_sort |
transcription coordinates histone amounts and genome content |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2021-07-01 |
description |
Accurate regulation of protein concentrations according to changes in cell volume that accompany growth and changes in biosynthetic capacity is an important component of cellular homeostasis. Here, using the model organism S. cerevisiae, the authors show how histone production is quantitatively coupled to genome content through the intrinsic properties of histone promoters. |
url |
https://doi.org/10.1038/s41467-021-24451-8 |
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