Clinical Characteristics of Inpatients with Childhood vs. Adolescent Anorexia Nervosa
We aimed to compare the clinical data at first presentation to inpatient treatment of children (<14 years) vs. adolescents (≥14 years) with anorexia nervosa (AN), focusing on duration of illness before hospital admission and body mass index (BMI) at admission and discharge, proven p...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-10-01
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| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/11/11/2593 |
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Article |
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DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Charlotte Jaite Katharina Bühren Brigitte Dahmen Astrid Dempfle Katja Becker Christoph U. Correll Karin M. Egberts Stefan Ehrlich Christian Fleischhaker Alexander von Gontard Freia Hahn David Kolar Michael Kaess Tanja Legenbauer Tobias J. Renner Ulrike Schulze Judith Sinzig Ellen Thomae Linda Weber Ida Wessing Gisela Antony Johannes Hebebrand Manuel Föcker Beate Herpertz-Dahlmann |
| spellingShingle |
Charlotte Jaite Katharina Bühren Brigitte Dahmen Astrid Dempfle Katja Becker Christoph U. Correll Karin M. Egberts Stefan Ehrlich Christian Fleischhaker Alexander von Gontard Freia Hahn David Kolar Michael Kaess Tanja Legenbauer Tobias J. Renner Ulrike Schulze Judith Sinzig Ellen Thomae Linda Weber Ida Wessing Gisela Antony Johannes Hebebrand Manuel Föcker Beate Herpertz-Dahlmann Clinical Characteristics of Inpatients with Childhood vs. Adolescent Anorexia Nervosa Nutrients anorexia nervosa children adolescents clinical characteristics bmi outcome |
| author_facet |
Charlotte Jaite Katharina Bühren Brigitte Dahmen Astrid Dempfle Katja Becker Christoph U. Correll Karin M. Egberts Stefan Ehrlich Christian Fleischhaker Alexander von Gontard Freia Hahn David Kolar Michael Kaess Tanja Legenbauer Tobias J. Renner Ulrike Schulze Judith Sinzig Ellen Thomae Linda Weber Ida Wessing Gisela Antony Johannes Hebebrand Manuel Föcker Beate Herpertz-Dahlmann |
| author_sort |
Charlotte Jaite |
| title |
Clinical Characteristics of Inpatients with Childhood vs. Adolescent Anorexia Nervosa |
| title_short |
Clinical Characteristics of Inpatients with Childhood vs. Adolescent Anorexia Nervosa |
| title_full |
Clinical Characteristics of Inpatients with Childhood vs. Adolescent Anorexia Nervosa |
| title_fullStr |
Clinical Characteristics of Inpatients with Childhood vs. Adolescent Anorexia Nervosa |
| title_full_unstemmed |
Clinical Characteristics of Inpatients with Childhood vs. Adolescent Anorexia Nervosa |
| title_sort |
clinical characteristics of inpatients with childhood vs. adolescent anorexia nervosa |
| publisher |
MDPI AG |
| series |
Nutrients |
| issn |
2072-6643 |
| publishDate |
2019-10-01 |
| description |
We aimed to compare the clinical data at first presentation to inpatient treatment of children (<14 years) vs. adolescents (≥14 years) with anorexia nervosa (AN), focusing on duration of illness before hospital admission and body mass index (BMI) at admission and discharge, proven predictors of the outcomes of adolescent AN. Clinical data at first admission and at discharge in 289 inpatients with AN (children: <i>n</i> = 72; adolescents: <i>n</i> = 217) from a German multicenter, web-based registry for consecutively enrolled patients with childhood and adolescent AN were analyzed. Inclusion criteria were a maximum age of 18 years, first inpatient treatment due to AN, and a BMI <10th BMI percentile at admission. Compared to adolescents, children with AN had a shorter duration of illness before admission (median: 6.0 months vs. 8.0 months, <i>p</i> = 0.004) and higher BMI percentiles at admission (median: 0.7 vs. 0.2, <i>p</i> = 0.004) as well as at discharge (median: 19.3 vs. 15.1, <i>p</i> = 0.011). Thus, in our study, children with AN exhibited clinical characteristics that have been associated with better outcomes, including higher admission and discharge BMI percentile. Future studies should examine whether these factors are actually associated with positive long-term outcomes in children. |
| topic |
anorexia nervosa children adolescents clinical characteristics bmi outcome |
| url |
https://www.mdpi.com/2072-6643/11/11/2593 |
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doaj-5b2d25ad716a46178d95871360d01edd2020-11-24T21:50:44ZengMDPI AGNutrients2072-66432019-10-011111259310.3390/nu11112593nu11112593Clinical Characteristics of Inpatients with Childhood vs. Adolescent Anorexia NervosaCharlotte Jaite0Katharina Bühren1Brigitte Dahmen2Astrid Dempfle3Katja Becker4Christoph U. Correll5Karin M. Egberts6Stefan Ehrlich7Christian Fleischhaker8Alexander von Gontard9Freia Hahn10David Kolar11Michael Kaess12Tanja Legenbauer13Tobias J. Renner14Ulrike Schulze15Judith Sinzig16Ellen Thomae17Linda Weber18Ida Wessing19Gisela Antony20Johannes Hebebrand21Manuel Föcker22Beate Herpertz-Dahlmann23Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charité–Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 13353 Berlin, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, RWTH Aachen, 52074 Aachen, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, RWTH Aachen, 52074 Aachen, GermanyInstitute of Medical Informatics and Statistics, Kiel University, 24105 Kiel, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University Marburg and University Hospital Marburg, 35039 Marburg, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Charité–Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 13353 Berlin, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wuerzburg, 97080 Wuerzburg, GermanyDepartment of Child and Adolescent Psychiatry & Division of Psychological & Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, 01307 Dresden, GermanyDepartment of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center Freiburg, 79104 Freiburg, GermanyDepartment of Child and Adolescent Psychiatry, Saarland University Hospital, 66421 Homburg, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LVR–Hospital Viersen, 41749 Viersen, GermanyDepartment of Child and Adolescent Psychiatry, University Medicine of the Johannes Gutenberg-University, 55131 Mainz, GermanyClinic of Child and Adolescent Psychiatry, Center for Psychosocial Medicine, University Hospital Heidelberg, 69115 Heidelberg, GermanyLWL University Hospital Hamm for Child and Adolescent Psychiatry, Ruhr University Bochum, 59071 Hamm, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Tuebingen, 72076 Tuebingen, GermanyDepartment of Child and Adolescent Psychiatry/Psychotherapy, University Hospital, University of Ulm, 89075 Ulm, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LVR-Klinik Bonn, 53111 Bonn, GermanyDepartment of Child and Adolescent Psychiatry, Faculty of Medicine, Technische Universität Dresden, 01307 Dresden, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University Marburg and University Hospital Marburg, 35039 Marburg, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Muenster, 48149 Muenster, GermanyCentral Information Office KKNMS, Philipps-University Marburg, 35112 Bellnhausen, GermanyDepartment of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Muenster, 48149 Muenster, GermanyDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, RWTH Aachen, 52074 Aachen, GermanyWe aimed to compare the clinical data at first presentation to inpatient treatment of children (<14 years) vs. adolescents (≥14 years) with anorexia nervosa (AN), focusing on duration of illness before hospital admission and body mass index (BMI) at admission and discharge, proven predictors of the outcomes of adolescent AN. Clinical data at first admission and at discharge in 289 inpatients with AN (children: <i>n</i> = 72; adolescents: <i>n</i> = 217) from a German multicenter, web-based registry for consecutively enrolled patients with childhood and adolescent AN were analyzed. Inclusion criteria were a maximum age of 18 years, first inpatient treatment due to AN, and a BMI <10th BMI percentile at admission. Compared to adolescents, children with AN had a shorter duration of illness before admission (median: 6.0 months vs. 8.0 months, <i>p</i> = 0.004) and higher BMI percentiles at admission (median: 0.7 vs. 0.2, <i>p</i> = 0.004) as well as at discharge (median: 19.3 vs. 15.1, <i>p</i> = 0.011). Thus, in our study, children with AN exhibited clinical characteristics that have been associated with better outcomes, including higher admission and discharge BMI percentile. Future studies should examine whether these factors are actually associated with positive long-term outcomes in children.https://www.mdpi.com/2072-6643/11/11/2593anorexia nervosachildrenadolescentsclinical characteristicsbmioutcome |