Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis

Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis

Abstract Aims Left ventricular (LV) dysfunction in viral myocarditis is attributed to myocardial inflammation and fibrosis, inducing acute and long‐time cardiac damage. Interventions are not established. On the basis of the link between inflammation, fibrosis, aldosterone, and extracellular matrix r...

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Bibliographic Details
Main Authors:	Carsten Tschöpe, Sophie Van Linthout, Sebastian Jäger, Robert Arndt, Tobias Trippel, Irene Müller, Ahmed Elsanhoury, Susanne Rutschow, Stefan D. Anker, Heinz‐Peter Schultheiss, Matthias Pauschinger, Frank Spillmann, Kathleen Pappritz
Format:	Article
Language:	English
Published:	Wiley 2020-10-01
Series:	ESC Heart Failure
Subjects:	Myocarditis Mineralocorticoid receptor inhibition Inflammation Fibrosis Coxsackievirus B3 COVID‐19
Online Access:	https://doi.org/10.1002/ehf2.12887

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