Bioengineered microfluidic blood-brain barrier models in oncology research

Bioengineered microfluidic blood-brain barrier models in oncology research

Metastasis is the major reason for most brain tumors with up to a 50% chance of occurrence in patients with other types of malignancies. Brain metastasis occurs if cancer cells succeed to cross the ‘blood-brain barrier’ (BBB). Moreover, changes in the structure and function of BBB can lead to the on...

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Bibliographic Details
Main Authors: Robin Augustine, Ahmad H. Aqel, Sumama Nuthana Kalva, K.S. Joshy, Ajisha Nayeem, Anwarul Hasan
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Translational Oncology
Subjects:
Blood-brain barrier
BBB models
Microfluidics
Microenvironment
Cancer
Metastasis
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321000796

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