Molecular screening of Plasmodium infections among migrant workers in Thailand

• Main Author: Kanyanan Kritsiriwuthinan , Warunee Ngrenngarmlert
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2011-12-01
• Series: Journal of Vector Borne Diseases
• Subjects: Malaria; migrant workers; semi-nested multiplex PCR; Thailand
• Online Access: http://www.mrcindia.org/journal/issues/484214.pdf

Background & objective: A cross-sectional study was conducted to determine the prevalence of Plasmodiuminfections among migrant workers in Thailand.Methods: A total of 241 migrants at Kanchanaburi, Pathumthani and Nakornpathom provinces of Thailand wererecruited in our surveillance. Blood samples were examined for human malaria parasites by using microscopyand semi-nested multiplex PCR (SnM-PCR).Results: Laboratory diagnosis revealed 6.2% total positive rate. As compared to microscopy (26.7%), SnM-PCRwas more sensitive (93.3%) for malaria. Plasmodium falciparum was predominant than P. vivax (53% : 40%,respectively). The majority of positive cases were from Myanmar workers who had low parasitaemia and withoutsymptoms. The highest prevalence (13.7%) was found among migrant workers from Kanchanaburi province inwestern Thailand.Conclusion: These findings indicate risk of malaria transmission from migrant workers. Malaria surveillanceshould be included in the health-screening program for migrants in Thailand to manage this health risk.