Tumor Resistance Explained by Hormesis

Tumor Resistance Explained by Hormesis

Enhanced drug (GDC 0449) resistance in a mouse model for human medulloblastoma is shown in the present paper to act via an hormetic response. This has significant implications, imposing constraints on the quantitative features of the dose response of the chemotherapeutic agent, affecting optimal stu...

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Bibliographic Details
Main Authors:	Edward J. Calabrese Ph.D., Marc A. Nascarella Ph.D.
Format:	Article
Language:	English
Published:	SAGE Publishing 2010-01-01
Series:	Dose-Response
Online Access:	https://doi.org/10.2203/dose-response.09-063.Calabrese

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