Use of Botulinum Neurotoxin in Ophthalmology
Botulinum neurotoxin (BoNT) is the first biological toxin used in the treatment of ophthalmic diseases and to decrease skin wrinkles as an aesthetic agent. When used appropriately, it weakens the force of muscular contraction and/or inhibits glandular secretion. The most common areas for botulinum t...
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Galenos Yayinevi
2016-12-01
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doaj-5b90cf2a7a894a069d35ec974cbb46332020-11-24T22:26:33ZengGalenos YayineviTürk Oftalmoloji Dergisi1300-06592147-26612016-12-0146628229010.4274/tjo.57701Use of Botulinum Neurotoxin in OphthalmologyEmel Başar0Ceyhun Arıcı1İstanbul University Cerrahpaşa Faculty of Medicine, Department of Ophthalmology, İstanbul, Turkeyİstanbul University Cerrahpaşa Faculty of Medicine, Department of Ophthalmology, İstanbul, TurkeyBotulinum neurotoxin (BoNT) is the first biological toxin used in the treatment of ophthalmic diseases and to decrease skin wrinkles as an aesthetic agent. When used appropriately, it weakens the force of muscular contraction and/or inhibits glandular secretion. The most common areas for botulinum toxin treatment are the upper face, including the glabella, forehead, brows, and lateral canthal lines or crow’s feet. By relaxing the muscles causing wrinkles, non-permanent results may be achieved with its use. BoNT has gained widespread use in a variety of ophthalmic diseases. The effect of BoNT is temporary, but the therapeutic benefit is usually maintained even after repeated injections. Treatment is usually well tolerated. Complications and side effects associated with the treatment are rare and temporary. Complications occur due to weakness (chemodenervation) of adjacent muscle groups, immunological mechanisms and injection technique. Current therapeutic indications, doses, complications and contraindications of BoNT use in the following disorders related to ophthalmology were investigated: aesthetic use, strabismus, blepharospasm, hemifacial spasm, eyelid retraction, entropion, lacrimal hypersecretion syndrome, and facial paralysis.http://www.oftalmoloji.org/article_12564/Use-Of-Botulinum-Neurotoxin-In-OphthalmologyBotulinum toxinblepharospasmhemifacial spasmstrabismus |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Emel Başar Ceyhun Arıcı |
spellingShingle |
Emel Başar Ceyhun Arıcı Use of Botulinum Neurotoxin in Ophthalmology Türk Oftalmoloji Dergisi Botulinum toxin blepharospasm hemifacial spasm strabismus |
author_facet |
Emel Başar Ceyhun Arıcı |
author_sort |
Emel Başar |
title |
Use of Botulinum Neurotoxin in Ophthalmology |
title_short |
Use of Botulinum Neurotoxin in Ophthalmology |
title_full |
Use of Botulinum Neurotoxin in Ophthalmology |
title_fullStr |
Use of Botulinum Neurotoxin in Ophthalmology |
title_full_unstemmed |
Use of Botulinum Neurotoxin in Ophthalmology |
title_sort |
use of botulinum neurotoxin in ophthalmology |
publisher |
Galenos Yayinevi |
series |
Türk Oftalmoloji Dergisi |
issn |
1300-0659 2147-2661 |
publishDate |
2016-12-01 |
description |
Botulinum neurotoxin (BoNT) is the first biological toxin used in the treatment of ophthalmic diseases and to decrease skin wrinkles as an aesthetic agent. When used appropriately, it weakens the force of muscular contraction and/or inhibits glandular secretion. The most common areas for botulinum toxin treatment are the upper face, including the glabella, forehead, brows, and lateral canthal lines or crow’s feet. By relaxing the muscles causing wrinkles, non-permanent results may be achieved with its use. BoNT has gained widespread use in a variety of ophthalmic diseases. The effect of BoNT is temporary, but the therapeutic benefit is usually maintained even after repeated injections. Treatment is usually well tolerated. Complications and side effects associated with the treatment are rare and temporary. Complications occur due to weakness (chemodenervation) of adjacent muscle groups, immunological mechanisms and injection technique. Current therapeutic indications, doses, complications and contraindications of BoNT use in the following disorders related to ophthalmology were investigated: aesthetic use, strabismus, blepharospasm, hemifacial spasm, eyelid retraction, entropion, lacrimal hypersecretion syndrome, and facial paralysis. |
topic |
Botulinum toxin blepharospasm hemifacial spasm strabismus |
url |
http://www.oftalmoloji.org/article_12564/Use-Of-Botulinum-Neurotoxin-In-Ophthalmology |
work_keys_str_mv |
AT emelbasar useofbotulinumneurotoxininophthalmology AT ceyhunarıcı useofbotulinumneurotoxininophthalmology |
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1725753119193694208 |