Use of Recombination-Mediated Genetic Engineering for Construction of Rescue Human Cytomegalovirus Bacterial Artificial Chromosome Clones

Use of Recombination-Mediated Genetic Engineering for Construction of Rescue Human Cytomegalovirus Bacterial Artificial Chromosome Clones

Bacterial artificial chromosome (BAC) technology has contributed immensely to manipulation of larger genomes in many organisms including large DNA viruses like human cytomegalovirus (HCMV). The HCMV BAC clone propagated and maintained inside E. coli allows for accurate recombinant virus generation....

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Bibliographic Details
Main Authors:	Kalpana Dulal, Benjamin Silver, Hua Zhu
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	Journal of Biomedicine and Biotechnology
Online Access:	http://dx.doi.org/10.1155/2012/357147

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