miR-214-3p-Sufu-GLI1 is a novel regulatory axis controlling inflammatory smooth muscle cell differentiation from stem cells and neointimal hyperplasia

miR-214-3p-Sufu-GLI1 is a novel regulatory axis controlling inflammatory smooth muscle cell differentiation from stem cells and neointimal hyperplasia

Abstract Background Inflammatory smooth muscle cells (iSMCs) generated from adventitial stem/progenitor cells (AdSPCs) have been recognised as a new player in cardiovascular disease, and microRNA-214-3p (miR-214-3p) has been implicated in mature vascular SMC functions and neointimal hyperplasia. Her...

Full description

Bibliographic Details
Main Authors: Shiping He, Feng Yang, Mei Yang, Weiwei An, Eithne Margaret Maguire, Qishan Chen, Rui Xiao, Wei Wu, Li Zhang, Wen Wang, Qingzhong Xiao
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Stem Cell Research & Therapy
Subjects:
Adventitia stem/progenitor cells
Neointima formation
Inflammatory smooth muscle cell
Smooth muscle cell differentiation
MicroRNA-214
MicroRNAs
Online Access:http://link.springer.com/article/10.1186/s13287-020-01989-w

Internet

http://link.springer.com/article/10.1186/s13287-020-01989-w

Similar Items