Histological-subtypes and anatomical location correlated in meningeal brain tumors (meningiomas)
Context: Not enough literature is available to suggest a link between the histological subtypes of intracranial meningeal brain tumors, called ‘meningiomas’ and their location of origin. Aim: The evidence of correlation between the anatomical location of the intracranial meningiomas and the histopat...
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doaj-5bad9fef192e4b74bcd2191f4fa5810f2021-04-02T11:33:00ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neurosciences in Rural Practice0976-31470976-31552014-07-01050324424910.1055/s-0039-1700321Histological-subtypes and anatomical location correlated in meningeal brain tumors (meningiomas)Abdul Rashid Bhat0Muhammed Afzal Wani1Altaf Rehman Kirmani2Altaf Umar Ramzan3Department of Neurosurgery, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, IndiaDepartment of Neurosurgery, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, IndiaDepartment of Neurosurgery, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, IndiaDepartment of Neurosurgery, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, IndiaContext: Not enough literature is available to suggest a link between the histological subtypes of intracranial meningeal brain tumors, called ‘meningiomas’ and their location of origin. Aim: The evidence of correlation between the anatomical location of the intracranial meningiomas and the histopathological grades will facilitate specific diagnosis and accurate treatment. Materials and Methods: The retrospective study was conducted in a single high-patient-inflow Neurosurgical Center, under a standard and uniform medical protocol, over a period of 30 years from December 1982 to December 2012. The records of all the operated 729 meningiomas were analyzed from the patient files in the Medical Records Department. The biodata, x-rays, angiography, computed tomography (CT) scans, imaging, histopathological reports, and mortality were evaluated and results drawn. Results: The uncommon histopathological types of meningiomas (16.88%) had common locations of origin in the sphenoid ridge, posterior parafalcine, jugular foramen, peritorcular and intraventricular regions, cerebellopontine angle, and tentorial and petroclival areas. The histopathological World Health Organization (WHO) Grade I (Benign Type) meningiomas were noted in 89.30%, WHO Grade II (Atypical Type) in 5.90%, and WHO Grade III (Malignant Type) in 4.80% of all meningiomas. Meningiomas of 64.60% were found in females, 47.32% were in the age group of 41-50 years, and 3.43% meningiomas were found in children. An overall mortality of 6.04% was noted. WHO Grade III (malignant meningiomas) carried a high mortality (25.71%) and the most common sites of meningiomas with high mortality were: The cerebellopontine angles, intraventricular region, sphenoid ridge, tuberculum sellae, and the posterior parafalcine areas. Conclusion: The correlation between the histological subtypes and the anatomical location of intracranial meningeal brain tumors, called meningiomas, is evident, but further research is required to establish the link.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1700321anatomical origincorrelationhistological typesintracranial meningiomas |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Abdul Rashid Bhat Muhammed Afzal Wani Altaf Rehman Kirmani Altaf Umar Ramzan |
spellingShingle |
Abdul Rashid Bhat Muhammed Afzal Wani Altaf Rehman Kirmani Altaf Umar Ramzan Histological-subtypes and anatomical location correlated in meningeal brain tumors (meningiomas) Journal of Neurosciences in Rural Practice anatomical origin correlation histological types intracranial meningiomas |
author_facet |
Abdul Rashid Bhat Muhammed Afzal Wani Altaf Rehman Kirmani Altaf Umar Ramzan |
author_sort |
Abdul Rashid Bhat |
title |
Histological-subtypes and anatomical location correlated in meningeal brain tumors (meningiomas) |
title_short |
Histological-subtypes and anatomical location correlated in meningeal brain tumors (meningiomas) |
title_full |
Histological-subtypes and anatomical location correlated in meningeal brain tumors (meningiomas) |
title_fullStr |
Histological-subtypes and anatomical location correlated in meningeal brain tumors (meningiomas) |
title_full_unstemmed |
Histological-subtypes and anatomical location correlated in meningeal brain tumors (meningiomas) |
title_sort |
histological-subtypes and anatomical location correlated in meningeal brain tumors (meningiomas) |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
series |
Journal of Neurosciences in Rural Practice |
issn |
0976-3147 0976-3155 |
publishDate |
2014-07-01 |
description |
Context: Not enough literature is available to suggest a link between the histological subtypes of intracranial meningeal brain tumors, called ‘meningiomas’ and their location of origin. Aim: The evidence of correlation between the anatomical location of the intracranial meningiomas and the histopathological grades will facilitate specific diagnosis and accurate treatment. Materials and Methods: The retrospective study was conducted in a single high-patient-inflow Neurosurgical Center, under a standard and uniform medical protocol, over a period of 30 years from December 1982 to December 2012. The records of all the operated 729 meningiomas were analyzed from the patient files in the Medical Records Department. The biodata, x-rays, angiography, computed tomography (CT) scans, imaging, histopathological reports, and mortality were evaluated and results drawn. Results: The uncommon histopathological types of meningiomas (16.88%) had common locations of origin in the sphenoid ridge, posterior parafalcine, jugular foramen, peritorcular and intraventricular regions, cerebellopontine angle, and tentorial and petroclival areas. The histopathological World Health Organization (WHO) Grade I (Benign Type) meningiomas were noted in 89.30%, WHO Grade II (Atypical Type) in 5.90%, and WHO Grade III (Malignant Type) in 4.80% of all meningiomas. Meningiomas of 64.60% were found in females, 47.32% were in the age group of 41-50 years, and 3.43% meningiomas were found in children. An overall mortality of 6.04% was noted. WHO Grade III (malignant meningiomas) carried a high mortality (25.71%) and the most common sites of meningiomas with high mortality were: The cerebellopontine angles, intraventricular region, sphenoid ridge, tuberculum sellae, and the posterior parafalcine areas. Conclusion: The correlation between the histological subtypes and the anatomical location of intracranial meningeal brain tumors, called meningiomas, is evident, but further research is required to establish the link. |
topic |
anatomical origin correlation histological types intracranial meningiomas |
url |
http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1700321 |
work_keys_str_mv |
AT abdulrashidbhat histologicalsubtypesandanatomicallocationcorrelatedinmeningealbraintumorsmeningiomas AT muhammedafzalwani histologicalsubtypesandanatomicallocationcorrelatedinmeningealbraintumorsmeningiomas AT altafrehmankirmani histologicalsubtypesandanatomicallocationcorrelatedinmeningealbraintumorsmeningiomas AT altafumarramzan histologicalsubtypesandanatomicallocationcorrelatedinmeningealbraintumorsmeningiomas |
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