Cadherin-11 localizes to focal adhesions and promotes cell–substrate adhesion
Cadherins are typically involved in cell-cell adhesion, however cadherin-11 promotes cell migration through an undefined mechanism. Langhe et al.show that cadherin-11 mediates adhesion to the cell matrix at focal adhesions through interaction with syndecan-4.
Main Authors: | Rahul P. Langhe, Tetyana Gudzenko, Michael Bachmann, Sarah F. Becker, Carina Gonnermann, Claudia Winter, Genevieve Abbruzzese, Dominique Alfandari, Marie-Claire Kratzer, Clemens M. Franz, Jubin Kashef |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms10909 |
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