Enhanced Cytochrome P450 IA1 Activity of Self-Assembled Rat Hepatocyte Spheroids

Primary rat hepatocytes can self-assemble to form multicellular spheroids when plated onto Primaria petri dishes. Spheroids have been observed to exhibit enhanced liver-specific functions and differentiated ultrastructure compared to monolayer cultures on dry collagen. With confocal scanning laser m...

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Bibliographic Details
Main Authors: Florence J. Wu, Julie R. Friend, Rory P. Remmel, Frank B. Cerra, Wei-Shou Hu
Format: Article
Language:English
Published: SAGE Publishing 1999-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979900800304