Enhanced Cytochrome P450 IA1 Activity of Self-Assembled Rat Hepatocyte Spheroids
Primary rat hepatocytes can self-assemble to form multicellular spheroids when plated onto Primaria petri dishes. Spheroids have been observed to exhibit enhanced liver-specific functions and differentiated ultrastructure compared to monolayer cultures on dry collagen. With confocal scanning laser m...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
1999-05-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.1177/096368979900800304 |