Bibliometric Analysis of ATAC-Seq and Its Use in Cancer Biology via Nucleic Acid Detection
Assay for transposase-accessible chromatin using sequencing (ATAC-seq) is associated with significant progress in biological research and has attracted increasing attention. However, the impact of ATAC-seq on cancer biology has not been objectively analyzed. We categorized 440 ATAC-seq publications...
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doaj-5bd9edef5a694a6c9eb53c088b1851612020-11-25T03:10:36ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2020-11-01710.3389/fmed.2020.584728584728Bibliometric Analysis of ATAC-Seq and Its Use in Cancer Biology via Nucleic Acid DetectionYu Zhao0Xianwen Zhang1Zhenhua Song2Danian Wei3Hong Wang4Hong Wang5Wei Chen6Guodong Sun7Weiying Ma8Kebing Chen9Department of Hematology, The Third Affiliated Hospital of Southern Medical University, Guangzhou, ChinaSchool of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaGuangdong Provincial Key Laboratory of Bone and Joint Degeneration Disease, Department of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital of Southern Medical University (Academy of Orthopedics of Guangdong Province), Guangzhou, ChinaGuangdong Provincial Key Laboratory of Bone and Joint Degeneration Disease, Department of Treatment Center for Traumatic Injuries, The Third Affiliated Hospital of Southern Medical University (Academy of Orthopedics of Guangdong Province), Guangzhou, ChinaGuangdong Provincial Key Laboratory of Bone and Joint Degeneration Disease, The Third Affiliated Hospital of Southern Medical University, Guangzhou, ChinaAcademy of Orthopedics of Guangdong Province, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Bone and Joint Degeneration Disease, Department of Musculoskeletal Oncology, The Third Affiliated Hospital of Southern Medical University (Academy of Orthopedics of Guangdong Province), Guangzhou, ChinaDepartment of Orthopedics, The First Affiliated Hospital of Jinan University, Guangzhou, ChinaDepartment of Anesthesiology, Sun Yat-sen Memorial Hospital, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Bone and Joint Degeneration Disease, Department of Spine Surgery, The Third Affiliated Hospital of Southern Medical University (Academy of Orthopedics of Guangdong Province), Guangzhou, ChinaAssay for transposase-accessible chromatin using sequencing (ATAC-seq) is associated with significant progress in biological research and has attracted increasing attention. However, the impact of ATAC-seq on cancer biology has not been objectively analyzed. We categorized 440 ATAC-seq publications according to the publication date, type, field, and country. R 3.6.2 was used to analyze the distribution of research fields. VOSviewer was used for country co-authorship and author co-authorship analyses, and GraphPad Prism 8 was used for correlation analyses of the factors that may affect the number of articles published in different countries. We found that ATAC-seq plays roles in carcinogenesis, anticancer immunity, targeted therapy, and metastasis risk predictions and is most frequently used in studies of leukemia among all types of cancer. We found a significantly strong correlation between the top 10 countries in terms of the number of publications and the gross expenditure on research and development (R&D), the number of universities, and the number of researchers. At present, ATAC-seq technology is undergoing a period of rapid development, making it inseparable from the emphasis and investment in scientific research by many countries. Collectively, ATAC-seq has advantages in the study of the cancer mechanisms because it can detect nucleic acids and thus has good application prospects in the field of cancer, especially in leukemia studies. As a country's economic strength increases and the emphasis on scientific research deepens, ATAC-seq will definitely play a more significant role in the field of cancer biology.https://www.frontiersin.org/articles/10.3389/fmed.2020.584728/fullATAC-seqopen chromatinbibliometric analysiscancer biologyleukemia |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yu Zhao Xianwen Zhang Zhenhua Song Danian Wei Hong Wang Hong Wang Wei Chen Guodong Sun Weiying Ma Kebing Chen |
spellingShingle |
Yu Zhao Xianwen Zhang Zhenhua Song Danian Wei Hong Wang Hong Wang Wei Chen Guodong Sun Weiying Ma Kebing Chen Bibliometric Analysis of ATAC-Seq and Its Use in Cancer Biology via Nucleic Acid Detection Frontiers in Medicine ATAC-seq open chromatin bibliometric analysis cancer biology leukemia |
author_facet |
Yu Zhao Xianwen Zhang Zhenhua Song Danian Wei Hong Wang Hong Wang Wei Chen Guodong Sun Weiying Ma Kebing Chen |
author_sort |
Yu Zhao |
title |
Bibliometric Analysis of ATAC-Seq and Its Use in Cancer Biology via Nucleic Acid Detection |
title_short |
Bibliometric Analysis of ATAC-Seq and Its Use in Cancer Biology via Nucleic Acid Detection |
title_full |
Bibliometric Analysis of ATAC-Seq and Its Use in Cancer Biology via Nucleic Acid Detection |
title_fullStr |
Bibliometric Analysis of ATAC-Seq and Its Use in Cancer Biology via Nucleic Acid Detection |
title_full_unstemmed |
Bibliometric Analysis of ATAC-Seq and Its Use in Cancer Biology via Nucleic Acid Detection |
title_sort |
bibliometric analysis of atac-seq and its use in cancer biology via nucleic acid detection |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Medicine |
issn |
2296-858X |
publishDate |
2020-11-01 |
description |
Assay for transposase-accessible chromatin using sequencing (ATAC-seq) is associated with significant progress in biological research and has attracted increasing attention. However, the impact of ATAC-seq on cancer biology has not been objectively analyzed. We categorized 440 ATAC-seq publications according to the publication date, type, field, and country. R 3.6.2 was used to analyze the distribution of research fields. VOSviewer was used for country co-authorship and author co-authorship analyses, and GraphPad Prism 8 was used for correlation analyses of the factors that may affect the number of articles published in different countries. We found that ATAC-seq plays roles in carcinogenesis, anticancer immunity, targeted therapy, and metastasis risk predictions and is most frequently used in studies of leukemia among all types of cancer. We found a significantly strong correlation between the top 10 countries in terms of the number of publications and the gross expenditure on research and development (R&D), the number of universities, and the number of researchers. At present, ATAC-seq technology is undergoing a period of rapid development, making it inseparable from the emphasis and investment in scientific research by many countries. Collectively, ATAC-seq has advantages in the study of the cancer mechanisms because it can detect nucleic acids and thus has good application prospects in the field of cancer, especially in leukemia studies. As a country's economic strength increases and the emphasis on scientific research deepens, ATAC-seq will definitely play a more significant role in the field of cancer biology. |
topic |
ATAC-seq open chromatin bibliometric analysis cancer biology leukemia |
url |
https://www.frontiersin.org/articles/10.3389/fmed.2020.584728/full |
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