Chemical Structures of 4-Oxo-Flavonoids in Relation to Inhibition of Oxidized Low-Density Lipoprotein (LDL)-Induced Vascular Endothelial Dysfunction

Chemical Structures of 4-Oxo-Flavonoids in Relation to Inhibition of Oxidized Low-Density Lipoprotein (LDL)-Induced Vascular Endothelial Dysfunction

Vascular endothelial dysfunction induced by oxidative stress has been demonstrated to be the initiation step of atherosclerosis (AS), and flavonoids may play an important role in AS prevention and therapy. Twenty-three flavonoids categorized into flavones, flavonols, isoflavones, and flavanones, all...

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Bibliographic Details
Main Authors: Man-Tian Mi, Qian-Yong Zhang, Jun-Dong Zhu, Yong Zhou, Hui Chang, Ting Zhang, Yu-Jie Fu, Chun-Ye Chen, Xin Jin, Long Yi
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:International Journal of Molecular Sciences
Subjects:
flavonoids
endothelial dysfunction
oxidized low-density lipoprotein
structure-activity analysis
atherosclerosis
reactive oxygen species
Online Access:http://www.mdpi.com/1422-0067/12/9/5471/

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