A novel direct co-culture assay analyzed by multicolor flow cytometry reveals context- and cell type-specific immunomodulatory effects of equine mesenchymal stromal cells.
The immunomodulatory potential of multipotent mesenchymal stromal cells (MSC) provides a basis for current and future regenerative therapies. In this study, we established an approach that allows to address the effects of pro-inflammatory stimulation and co-culture with MSC on different specific leu...
Main Authors: | Aline Hillmann, Felicitas Paebst, Walter Brehm, Daniel Piehler, Susanna Schubert, Attila Tárnok, Janina Burk |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0218949 |
Similar Items
-
Comparative Characterization of Human and Equine Mesenchymal Stromal Cells: A Basis for Translational Studies in the Equine Model
by: Aline Hillmann, et al.
Published: (2016-01-01) -
Long-Term Cell Tracking following Local Injection of Mesenchymal Stromal Cells in the Equine Model of Induced Tendon Disease
by: Janina Burk, et al.
Published: (2016-12-01) -
Gene expression of tendon markers in mesenchymal stromal cells derived from different sources
by: Burk, Janina, et al.
Published: (2014) -
Effects of mesenchymal stromal cells versus serum on tendon healing in a controlled experimental trial in an equine model
by: A. B. Ahrberg, et al.
Published: (2018-07-01) -
Phenotypic and immunomodulatory properties of equine cord blood-derived mesenchymal stromal cells.
by: Laurence Tessier, et al.
Published: (2015-01-01)