Small cell carcinoma of prostate presenting with Cushing′s syndrome

• Main Authors: Selahattin Çaliskan, Gülistan Gümrükçü, Abdurrahman Yigit
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2015-01-01
• Series: Medical Journal of Dr. D.Y. Patil University
• Subjects: Cushing′s syndrome; prostate cancer; small cell
• Online Access: http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2015;volume=8;issue=2;spage=234;epage=236;aulast=Çaliskan

Small cell carcinoma of prostate (SCPCa) was initially described by Wenk et al. in 1977. SCPCa is a very rare cancer that accounts for only 0.5-2% of all prostate carcinomas. Although, this pathology is usually accompanied with prostate adenocarcinomas, there are a few hypotheses about the origin of SCPCa. Poorly differentiated acinar adenocarcinoma must be distinguished from SCPCa in histopathological examination. These patients may present with different paraneoplastic syndromes. Early diagnosis is very important because of the aggressive tumor behavior. Here, we report a patient who presented with Cushing syndrome and thereafter diagnosed with SCPCa.