Ketogenic Metabolic Therapy, Without Chemo or Radiation, for the Long-Term Management of IDH1-Mutant Glioblastoma: An 80-Month Follow-Up Case Report

Ketogenic Metabolic Therapy, Without Chemo or Radiation, for the Long-Term Management of IDH1-Mutant Glioblastoma: An 80-Month Follow-Up Case Report

Background: Successful treatment of glioblastoma (GBM) remains futile despite decades of intense research. GBM is similar to most other malignant cancers in requiring glucose and glutamine for growth, regardless of histological or genetic heterogeneity. Ketogenic metabolic therapy (KMT) is a non-tox...

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Bibliographic Details
Main Authors: Thomas N. Seyfried, Aditya G. Shivane, Miriam Kalamian, Joseph C. Maroon, Purna Mukherjee, Giulio Zuccoli
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Nutrition
Subjects:
standard of care
glycolysis
glutaminolysis
fasting
mitochondrial substrate level phosphorylation (mSLP)
2-hydroxyglutarate
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2021.682243/full

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https://www.frontiersin.org/articles/10.3389/fnut.2021.682243/full

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