COVID-19 and Obesity: Epidemiology, Pathogenesis and Treatment

• Main Authors: Zhu X, Yang L, Huang K
• Format: Article
• Language: English
• Published: Dove Medical Press 2020-12-01
• Series: Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy
• Subjects: covid-19; obesity，sars-cov-2
• Online Access: https://www.dovepress.com/covid-19-and-obesity-epidemiology-pathogenesis-and-treatment-peer-reviewed-article-DMSO
• ISSN: 1178-7007

Xinyu Zhu,1,2,* Liu Yang,1,2,* Kai Huang1,2 1Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China; 2Clinical Center for Human Genomic Research, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kai HuangDepartment of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Ave, Wuhan, Hubei 430022, People’s Republic of ChinaEmail [e-mail]: The growing prevalence of overweight and obesity has been a worldwide public health issue. During the COVID-19 pandemic, obesity is associated with a higher risk of severity and a worse clinical outcome of SARS-COV-2 infection. This may be because of the chronic low-grade inflammation, impaired immune response and metabolic disorders in obese patients. In this narrative review, we have summarized the association between obesity and COVID-19 and discussed the potential pathogenesis and treatment in these patients. This work may provide practical suggestions on the clinical management of obese COVID-19 patients.Keywords: COVID-19, obesity, SARS-COV-2