Lymphocyte Activation Gene-3 (LAG-3) negatively regulates environmentally-induced autoimmunity.

Lymphocyte Activation Gene-3 (LAG-3) negatively regulates environmentally-induced autoimmunity.

Environmental factors including drugs, mineral oils and heavy metals such as lead, gold and mercury are triggers of autoimmune diseases in animal models or even in occupationally exposed humans. After exposure to subtoxic levels of mercury (Hg), genetically susceptible strains of mice develop an aut...

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Bibliographic Details
Main Authors: Vibha Jha, Creg J Workman, Tracy L McGaha, Liping Li, Jaya Vas, Dario A A Vignali, Marc Monestier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4133201?pdf=render

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