Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum
Two of bioactive natural products were founded in a brown alga, Sargassum fulvellum. After isolation and purification, the molecular structures of these two products were investigated by NMR spectroscopy and GC-mass spectroscopy. The two compounds were identified to be 1-O-palmitoyl-2-O-oleoyl-3-O-(...
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| Format: | Article |
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MDPI AG
2009-04-01
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| Series: | Marine Drugs |
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| Online Access: | http://www.mdpi.com/1660-3397/7/2/85/ |
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doaj-5c326c68a0574e6db699921213cf7d202020-11-24T21:35:06ZengMDPI AGMarine Drugs1660-33972009-04-0172859410.3390/md7020085Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellumBin BaoXianwen HuKeiji HasumiXichang WangHui PengWenhui WuTwo of bioactive natural products were founded in a brown alga, Sargassum fulvellum. After isolation and purification, the molecular structures of these two products were investigated by NMR spectroscopy and GC-mass spectroscopy. The two compounds were identified to be 1-O-palmitoyl-2-O-oleoyl-3-O-(α-D-glucopyranosyl) –glycerol (POGG) and 1-O-myristoyl-2-O-oleoyl-3-O-(α-D-glucopyranosyl) – glycerol (MOGG) which were obtained from Sargassum fulvellum for the first time. POGG and MOGG showed fibrinolytic activity in the reaction system of pro-u-PA and plasminogen. http://www.mdpi.com/1660-3397/7/2/85/fibrinolytic activityNMRglucopyranosyldiacylglycerolstructure determinationSargassum fulvellum |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Bin Bao Xianwen Hu Keiji Hasumi Xichang Wang Hui Peng Wenhui Wu |
| spellingShingle |
Bin Bao Xianwen Hu Keiji Hasumi Xichang Wang Hui Peng Wenhui Wu Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum Marine Drugs fibrinolytic activity NMR glucopyranosyldiacylglycerol structure determination Sargassum fulvellum |
| author_facet |
Bin Bao Xianwen Hu Keiji Hasumi Xichang Wang Hui Peng Wenhui Wu |
| author_sort |
Bin Bao |
| title |
Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum |
| title_short |
Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum |
| title_full |
Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum |
| title_fullStr |
Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum |
| title_full_unstemmed |
Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum |
| title_sort |
fibrinolytic compounds isolated from a brown alga, sargassum fulvellum |
| publisher |
MDPI AG |
| series |
Marine Drugs |
| issn |
1660-3397 |
| publishDate |
2009-04-01 |
| description |
Two of bioactive natural products were founded in a brown alga, Sargassum fulvellum. After isolation and purification, the molecular structures of these two products were investigated by NMR spectroscopy and GC-mass spectroscopy. The two compounds were identified to be 1-O-palmitoyl-2-O-oleoyl-3-O-(α-D-glucopyranosyl) –glycerol (POGG) and 1-O-myristoyl-2-O-oleoyl-3-O-(α-D-glucopyranosyl) – glycerol (MOGG) which were obtained from Sargassum fulvellum for the first time. POGG and MOGG showed fibrinolytic activity in the reaction system of pro-u-PA and plasminogen. |
| topic |
fibrinolytic activity NMR glucopyranosyldiacylglycerol structure determination Sargassum fulvellum |
| url |
http://www.mdpi.com/1660-3397/7/2/85/ |
| work_keys_str_mv |
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1725946614701359104 |