The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse

The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse

The ribbon is the structural hallmark of cochlear inner hair cell (IHC) afferent synapses, yet its role in information transfer to spiral ganglion neurons (SGNs) remains unclear. We investigated the ribbon’s contribution to IHC synapse formation and function using KO mice lacking RIBEYE. Despite los...

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Bibliographic Details
Main Authors: Lars Becker, Michael E Schnee, Mamiko Niwa, Willy Sun, Stephan Maxeiner, Sara Talaei, Bechara Kachar, Mark A Rutherford, Anthony J Ricci
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-01-01
Series:eLife
Subjects:
synaptic ribbons
hair cells
ribeye
auditory
multivesicular release
synaptic transmission
Online Access:https://elifesciences.org/articles/30241

Internet

https://elifesciences.org/articles/30241

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