Comedone switch and reverse nella patogenesi e nel trattamento dell’acne. Un ruolo per la silimarina?

Comedone switch and reverse nella patogenesi e nel trattamento dell’acne. Un ruolo per la silimarina?

Recent developments in the understanding of pathophysiology of acne are creating new opportunities in the treatment of this disease. In this brief review, we illustrate the role of local inflammation, and LRIG1+ cells in the development of comedone switch, and the potential of silimarin to counter...

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Bibliographic Details
Main Authors: Stefano Veraldi, Mauro Barbareschi
Format: Article
Language:English
Published: AboutScience Srl 2020-09-01
Series:AboutOpen
Subjects:
Acne
Comedone switch
Silybum marianum
Online Access:https://journals.aboutscience.eu/index.php/aboutopen/article/view/2175
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spelling doaj-5c5424b554d348a98aebc89866980d702020-11-25T03:27:55ZengAboutScience SrlAboutOpen2465-26282020-09-017110.33393/abtpn.2020.2175Comedone switch and reverse nella patogenesi e nel trattamento dell’acne. Un ruolo per la silimarina?Stefano Veraldi0Mauro Barbareschi1Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano - ItalyDipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano - Italy Recent developments in the understanding of pathophysiology of acne are creating new opportunities in the treatment of this disease. In this brief review, we illustrate the role of local inflammation, and LRIG1+ cells in the development of comedone switch, and the potential of silimarin to counteract this process and favour comedone reverse. Preliminary data using Silybum marianum in different studies have shown promising results. Further data from ongoing studies will clarify its role in the long-term treatment of patients with acne.  https://journals.aboutscience.eu/index.php/aboutopen/article/view/2175AcneComedone switchSilybum marianum
collection DOAJ
language English
format Article
sources DOAJ
author Stefano Veraldi
Mauro Barbareschi
spellingShingle Stefano Veraldi
Mauro Barbareschi
Comedone switch and reverse nella patogenesi e nel trattamento dell’acne. Un ruolo per la silimarina?
AboutOpen
Acne
Comedone switch
Silybum marianum
author_facet Stefano Veraldi
Mauro Barbareschi
author_sort Stefano Veraldi
title Comedone switch and reverse nella patogenesi e nel trattamento dell’acne. Un ruolo per la silimarina?
title_short Comedone switch and reverse nella patogenesi e nel trattamento dell’acne. Un ruolo per la silimarina?
title_full Comedone switch and reverse nella patogenesi e nel trattamento dell’acne. Un ruolo per la silimarina?
title_fullStr Comedone switch and reverse nella patogenesi e nel trattamento dell’acne. Un ruolo per la silimarina?
title_full_unstemmed Comedone switch and reverse nella patogenesi e nel trattamento dell’acne. Un ruolo per la silimarina?
title_sort comedone switch and reverse nella patogenesi e nel trattamento dell’acne. un ruolo per la silimarina?
publisher AboutScience Srl
series AboutOpen
issn 2465-2628
publishDate 2020-09-01
description Recent developments in the understanding of pathophysiology of acne are creating new opportunities in the treatment of this disease. In this brief review, we illustrate the role of local inflammation, and LRIG1+ cells in the development of comedone switch, and the potential of silimarin to counteract this process and favour comedone reverse. Preliminary data using Silybum marianum in different studies have shown promising results. Further data from ongoing studies will clarify its role in the long-term treatment of patients with acne.  
topic Acne
Comedone switch
Silybum marianum
url https://journals.aboutscience.eu/index.php/aboutopen/article/view/2175
work_keys_str_mv AT stefanoveraldi comedoneswitchandreversenellapatogenesieneltrattamentodellacneunruoloperlasilimarina
AT maurobarbareschi comedoneswitchandreversenellapatogenesieneltrattamentodellacneunruoloperlasilimarina
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