SK Channel Modulates Synaptic Plasticity by Tuning CaMKIIα/β Dynamics

SK Channel Modulates Synaptic Plasticity by Tuning CaMKIIα/β Dynamics

N-Methyl-D-Aspartate Receptor 1 (NMDAR)-linked Ca++ current represents a significant percentage of post-synaptic transient that modulates synaptic strength and is pertinent to dendritic spine plasticity. In the hippocampus, Ca++ transient produced by glutamatergic ionotropic neurotransmission facili...

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Bibliographic Details
Main Authors: Amita Shrestha, Razia Sultana, Charles C. Lee, Olalekan M. Ogundele
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
NMDAR-GluN1
SK2/3
CaMKIIα
hippocampus
ISI
firing rate
Online Access:https://www.frontiersin.org/article/10.3389/fnsyn.2019.00018/full

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