miR-503/Apelin-12 mediates high glucose-induced microvascular endothelial cells injury via JNK and p38MAPK signaling pathway
Introduction: Diabetic patients are often accompanied by complications of diabetic vascular disease, which could lead to heart failure or stroke. In this work, we explored the role of miR-503/Apelin-12 in diabetic angiopathy (DA) in vitro. Methods: ELISA and qPCR were applied to assess the expressio...
Main Authors: | Kai Chen, Xin-Lan Zhao, Lang-Bo Li, Ling-Yun Huang, Zhuo Tang, Juan Luo, Li Yang, Ai-Ping Qin, Fang Hu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-06-01
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Series: | Regenerative Therapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352320419301592 |
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