Causes and Consequences of Age-Related Changes in DNA Methylation: A Role for ROS?
Recent genome-wide analysis of C-phosphate-G (CpG) sites has shown that the DNA methylome changes with increasing age, giving rise to genome-wide hypomethylation with site‑specific incidences of hypermethylation. This notion has received a lot of attention, as it potentially explains why aged organi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2014-06-01
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| Series: | Biology |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2079-7737/3/2/403 |