Beneficial effects of running exercise on hippocampal microglia and neuroinflammation in chronic unpredictable stress-induced depression model rats
Abstract Running exercise has been shown to relieve symptoms of depression, but the mechanisms underlying the antidepressant effects are unclear. Microglia and concomitant dysregulated neuroinflammation play a pivotal role in the pathogenesis of depression. However, the effects of running exercise o...
Main Authors: | Kai Xiao, Yanmin Luo, Xin Liang, Jing Tang, Jin Wang, Qian Xiao, Yingqiang Qi, Yue Li, Peilin Zhu, Hao Yang, Yuhan Xie, Hong Wu, Yong Tang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-09-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-021-01571-9 |
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