<b>Metabolic modeling and comparative biochemistry in glyoxylate cycle
Glyoxylate cycle in fatty acid catabolism enhances net production of oxaloacetate, a substrate for gluconeogenesis, in certain bacteria, invertebrates and oilseed in the growth stage. A theoretical model was developed to calculate ATP amount produced in each step of the catabolic pathway, taking int...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universidade Estadual de Maringá
2016-07-01
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| Series: | Acta Scientiarum : Biological Sciences |
| Subjects: | |
| Online Access: | http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/24597 |
| Summary: | Glyoxylate cycle in fatty acid catabolism enhances net production of oxaloacetate, a substrate for gluconeogenesis, in certain bacteria, invertebrates and oilseed in the growth stage. A theoretical model was developed to calculate ATP amount produced in each step of the catabolic pathway, taking into account the fatty acid’s hydrocarbon chain size. Results showed a decrease in energy efficiency in glyoxylate cycle when compared to animal metabolism. Although the glyoxylate cycle provides evolutionary adaptations, it determines a smaller amount of energy produced per carbon atom when compared to animal catabolism of fatty acids. |
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| ISSN: | 1679-9283 1807-863X |