Peripartum Heart Failure due to Primary Pulmonary Hypertension: Two Case Reports

Objective: Primary pulmonary hypertension (PPH) with pregnancy can result in peripartum heart failure and a high mortality rate. We report two cases of fatal PPH in pregnant women. Case Reports: From July 1992 to July 2002, two pregnant women with PPH were treated in our hospital. Case 1 was a 24-ye...

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Main Authors: Chung-Chang Shen, Te-Yao Hsu, Cherng-Jau Roan, Shiuh-Young Chang
Format: Article
Language:English
Published: Elsevier 2004-09-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455909600747
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spelling doaj-5cb19fe0c9594e06977f4bb5dbf3f6852020-11-24T23:47:20ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592004-09-0143315115410.1016/S1028-4559(09)60074-7Peripartum Heart Failure due to Primary Pulmonary Hypertension: Two Case ReportsChung-Chang ShenTe-Yao HsuCherng-Jau RoanShiuh-Young ChangObjective: Primary pulmonary hypertension (PPH) with pregnancy can result in peripartum heart failure and a high mortality rate. We report two cases of fatal PPH in pregnant women. Case Reports: From July 1992 to July 2002, two pregnant women with PPH were treated in our hospital. Case 1 was a 24-year-old primigravida, referred to our institution at 33 weeks of gestation because of signs of heart failure. She delivered a male baby by emergency cesarean section under general anesthesia. Five hours later, she developed severe systemic hypotension and died of cardiovascular collapse despite aggressive treatment and intensive care. Case 2 was a 29-year-old para 0 gravida 1 woman. She had been transferred to our hospital at 34 weeks of gestation, when fatigue, increasing dyspnea, orthopnea, tachycardia, chest pain, and peripheral cyanosis were found in our emergency department. She delivered a male baby by cesarean section under general anesthesia. Four hours later, she suddenly developed cyanosis and tachycardia, followed by electromechanical dissociation. All attempts at resuscitation were unsuccessful, and cardiac arrest ensued. Conclusion: We suggest that cesarean section be carried out with the help of the intensive care unit since transportation of the patient from the operating theatre to the intensive care unit is time-consuming and may result in deterioration of the patient's condition. A multidisciplinary team approach to management in the second trimester may reduce the high mortality rate.http://www.sciencedirect.com/science/article/pii/S1028455909600747primary pulmonary hypertensionperipartum heart failure
collection DOAJ
language English
format Article
sources DOAJ
author Chung-Chang Shen
Te-Yao Hsu
Cherng-Jau Roan
Shiuh-Young Chang
spellingShingle Chung-Chang Shen
Te-Yao Hsu
Cherng-Jau Roan
Shiuh-Young Chang
Peripartum Heart Failure due to Primary Pulmonary Hypertension: Two Case Reports
Taiwanese Journal of Obstetrics & Gynecology
primary pulmonary hypertension
peripartum heart failure
author_facet Chung-Chang Shen
Te-Yao Hsu
Cherng-Jau Roan
Shiuh-Young Chang
author_sort Chung-Chang Shen
title Peripartum Heart Failure due to Primary Pulmonary Hypertension: Two Case Reports
title_short Peripartum Heart Failure due to Primary Pulmonary Hypertension: Two Case Reports
title_full Peripartum Heart Failure due to Primary Pulmonary Hypertension: Two Case Reports
title_fullStr Peripartum Heart Failure due to Primary Pulmonary Hypertension: Two Case Reports
title_full_unstemmed Peripartum Heart Failure due to Primary Pulmonary Hypertension: Two Case Reports
title_sort peripartum heart failure due to primary pulmonary hypertension: two case reports
publisher Elsevier
series Taiwanese Journal of Obstetrics & Gynecology
issn 1028-4559
publishDate 2004-09-01
description Objective: Primary pulmonary hypertension (PPH) with pregnancy can result in peripartum heart failure and a high mortality rate. We report two cases of fatal PPH in pregnant women. Case Reports: From July 1992 to July 2002, two pregnant women with PPH were treated in our hospital. Case 1 was a 24-year-old primigravida, referred to our institution at 33 weeks of gestation because of signs of heart failure. She delivered a male baby by emergency cesarean section under general anesthesia. Five hours later, she developed severe systemic hypotension and died of cardiovascular collapse despite aggressive treatment and intensive care. Case 2 was a 29-year-old para 0 gravida 1 woman. She had been transferred to our hospital at 34 weeks of gestation, when fatigue, increasing dyspnea, orthopnea, tachycardia, chest pain, and peripheral cyanosis were found in our emergency department. She delivered a male baby by cesarean section under general anesthesia. Four hours later, she suddenly developed cyanosis and tachycardia, followed by electromechanical dissociation. All attempts at resuscitation were unsuccessful, and cardiac arrest ensued. Conclusion: We suggest that cesarean section be carried out with the help of the intensive care unit since transportation of the patient from the operating theatre to the intensive care unit is time-consuming and may result in deterioration of the patient's condition. A multidisciplinary team approach to management in the second trimester may reduce the high mortality rate.
topic primary pulmonary hypertension
peripartum heart failure
url http://www.sciencedirect.com/science/article/pii/S1028455909600747
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