Establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsion
This study aimed to establish nomograms to preoperatively predict the possibility of testicular salvage (TS) in patients with testicular torsion. The clinical data of 204 patients with testicular torsion diagnosed at Xijing Hospital and Tangdu Hospital (Xi'an, China) between August 2008 and Nov...
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Wolters Kluwer Medknow Publications
2021-01-01
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doaj-5cc3a9ea176f4ce4bcd29416a9d50d472021-02-03T05:45:41ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622021-01-012319710210.4103/aja.aja_31_20Establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsionWan-Xiang ZhengGuang-Dong HouWei ZhangDi WeiXue-Lin GaoMei-Hong ChenLu-Guang HuangFei YanGeng ZhangLei YuFei LiuBo ZhangJian-Lin YuanThis study aimed to establish nomograms to preoperatively predict the possibility of testicular salvage (TS) in patients with testicular torsion. The clinical data of 204 patients with testicular torsion diagnosed at Xijing Hospital and Tangdu Hospital (Xi'an, China) between August 2008 and November 2019 were retrospectively analyzed. Univariate and multivariate logistic regression analyses were used to determine the independent predictors of TS. Based on multivariate regression coefficients, nomograms to predict possibility of TS were established. The predictive ability of the nomograms was internally validated by receiver operating characteristic (ROC) curves and calibration plots. The duration of symptoms ranged from 2 h to 1 month, with a median of 3.5 days. Thirty (14.7%) patients underwent surgical reduction and contralateral orchiopexy, while the remaining 174 (85.3%) underwent orchiectomy and contralateral orchiopexy. Finally, long symptom duration was an independent risk predictor for TS, while visible intratesticular blood flow and homogeneous testicular echotexture under color Doppler ultrasound were independent protective predictors. Internal validation showed that the nomograms, which were established by integrating these three predictive factors, had good discrimination ability in predicting the possibility of TS (areas under the ROC curves were 0.851 and 0.828, respectively). The calibration plots showed good agreement between the nomogram-predicted possibility of TS and the actual situation. In conclusion, this brief preoperative prediction tool will help clinicians to quickly determine the urgency of surgical exploration.http://www.ajandrology.com/article.asp?issn=1008-682X;year=2021;volume=23;issue=1;spage=97;epage=102;aulast=nomogram; testicular salvage; testicular torsion |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Wan-Xiang Zheng Guang-Dong Hou Wei Zhang Di Wei Xue-Lin Gao Mei-Hong Chen Lu-Guang Huang Fei Yan Geng Zhang Lei Yu Fei Liu Bo Zhang Jian-Lin Yuan |
spellingShingle |
Wan-Xiang Zheng Guang-Dong Hou Wei Zhang Di Wei Xue-Lin Gao Mei-Hong Chen Lu-Guang Huang Fei Yan Geng Zhang Lei Yu Fei Liu Bo Zhang Jian-Lin Yuan Establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsion Asian Journal of Andrology nomogram; testicular salvage; testicular torsion |
author_facet |
Wan-Xiang Zheng Guang-Dong Hou Wei Zhang Di Wei Xue-Lin Gao Mei-Hong Chen Lu-Guang Huang Fei Yan Geng Zhang Lei Yu Fei Liu Bo Zhang Jian-Lin Yuan |
author_sort |
Wan-Xiang Zheng |
title |
Establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsion |
title_short |
Establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsion |
title_full |
Establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsion |
title_fullStr |
Establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsion |
title_full_unstemmed |
Establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsion |
title_sort |
establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsion |
publisher |
Wolters Kluwer Medknow Publications |
series |
Asian Journal of Andrology |
issn |
1008-682X 1745-7262 |
publishDate |
2021-01-01 |
description |
This study aimed to establish nomograms to preoperatively predict the possibility of testicular salvage (TS) in patients with testicular torsion. The clinical data of 204 patients with testicular torsion diagnosed at Xijing Hospital and Tangdu Hospital (Xi'an, China) between August 2008 and November 2019 were retrospectively analyzed. Univariate and multivariate logistic regression analyses were used to determine the independent predictors of TS. Based on multivariate regression coefficients, nomograms to predict possibility of TS were established. The predictive ability of the nomograms was internally validated by receiver operating characteristic (ROC) curves and calibration plots. The duration of symptoms ranged from 2 h to 1 month, with a median of 3.5 days. Thirty (14.7%) patients underwent surgical reduction and contralateral orchiopexy, while the remaining 174 (85.3%) underwent orchiectomy and contralateral orchiopexy. Finally, long symptom duration was an independent risk predictor for TS, while visible intratesticular blood flow and homogeneous testicular echotexture under color Doppler ultrasound were independent protective predictors. Internal validation showed that the nomograms, which were established by integrating these three predictive factors, had good discrimination ability in predicting the possibility of TS (areas under the ROC curves were 0.851 and 0.828, respectively). The calibration plots showed good agreement between the nomogram-predicted possibility of TS and the actual situation. In conclusion, this brief preoperative prediction tool will help clinicians to quickly determine the urgency of surgical exploration. |
topic |
nomogram; testicular salvage; testicular torsion |
url |
http://www.ajandrology.com/article.asp?issn=1008-682X;year=2021;volume=23;issue=1;spage=97;epage=102;aulast= |
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