Enhancement of solubility of albendazole by complexation with β-cyclodextrin

Enhancement of solubility of albendazole by complexation with β-cyclodextrin

A high dosage of albendazole (ABZ) is required for treating systemic helminthe infections because of its low solubility. Aiming at increasing ABZ solubility, complexation with beta-cyclodextrin (β-CD) using aqueous and acetic acid solutions as ABZ solubilizer was studied. In aqueous &#9...

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Bibliographic Details
Main Authors:	C. Moriwaki, G. L. Costa, C. N. Ferracini, F. F. de Moraes, G. M. Zanin, E. A. G. Pineda, G. Matioli
Format:	Article
Language:	English
Published:	Brazilian Society of Chemical Engineering 2008-06-01
Series:	Brazilian Journal of Chemical Engineering
Subjects:	Albendazole Cyclodextrins β-cyclodextrin Complexation Solubility
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322008000200005

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