PedWiz: A web-based tool for pedigree informatics

• Main Authors: Yeunjoo E. Song, Robert C Elston
• Format: Article
• Language: English
• Published: Frontiers Media S.A. 2013-09-01
• Series: Frontiers in Genetics
• Subjects: Informatics; pedigree; identity-by-descent; genetic similarity; relative pairs; family data
• Online Access: http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00189/full

A novel web-based tool PedWiz that pipelines the informatics process for pedigree data is introduced. PedWiz is designed to assist researchers in the analysis of pedigree data. It provides a convenient tool for pedigree informatics: descriptive statistics, relative pairs, genetic similarity coefficients, the variance-covariance matrix for three estimated coefficients of allele identical-by-descent sharing as well as mean allele sharing, a plot of the pedigree structures, and a visualization of the identity coefficients. With a renewed interest in linkage and other family-based methods, PedWiz will be a valuable tool for the analysis of family data.