Smp38 MAP Kinase Regulation in Schistosoma mansoni: Roles in Survival, Oviposition, and Protection Against Oxidative Stress

Smp38 MAP Kinase Regulation in Schistosoma mansoni: Roles in Survival, Oviposition, and Protection Against Oxidative Stress

Eukaryotic protein kinases (ePKs) are good medical targets for drug development in different biological systems. ePKs participate in many cellular processes, including the p38 MAPK regulation of homeostasis upon oxidative stress. We propose to assess the role of Smp38 MAPK signaling pathway in Schis...

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Bibliographic Details
Main Authors: Lívia das Graças Amaral Avelar, Sandra Grossi Gava, Renata Heisler Neves, Mercedes Carolina Soares Silva, Neusa Araújo, Naiara Clemente Tavares, Assmaa El Khal, Ana Carolina Alves Mattos, José Roberto Machado-Silva, Guilherme Oliveira, Marina de Moraes Mourão
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
Schistosoma mansoni
p38 MAPK
signaling pathways
development
oviposition
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00021/full

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