Tang-Nai-Kang alleviates pre-diabetes and metabolic disorders and induces a gene expression switch toward fatty acid oxidation in SHR.Cg-Leprcp/NDmcr rats.

Increased energy intake and reduced physical activity can lead to obesity, diabetes and metabolic syndrome. Transcriptional modulation of metabolic networks has become a focus of current drug discovery research into the prevention and treatment of metabolic disorders associated with energy surplus a...

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Main Authors: Linyi Li, Hisae Yoshitomi, Ying Wei, Lingling Qin, Jingxin Zhou, Tunhai Xu, Xinli Wu, Tian Zhou, Wen Sun, Xiangyu Guo, Lili Wu, Haiyan Wang, Yan Zhang, Chunna Li, Tonghua Liu, Ming Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0122024