Scleredema of Buschke associated with difficult-to-control type 2 diabetes mellitus

• Main Authors: Luciana Rodino Lemes, Gabriele Medina Vilela, Sandra Maria Barbosa Durães, Enoi Aparecida Guedes Vilar
• Format: Article
• Language: English
• Published: Associação Médica Brasileira 2016-06-01
• Series: Revista da Associação Médica Brasileira
• Subjects: escleredema do adulto; diabetes mellitus; dorso
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016000300199&lng=en&tlng=en

SUMMARY Scleredema of Buschke (SB) is a rare disorder of connective tissue characterized by diffuse non-pitting induration of the skin, mainly on the cervical, deltoid and dorsal regions. It is a cutaneous mucinosis of unknown etiology and is associated with bacterial or viral infections, hematological disorders and diabetes mellitus. Histopathological examination shows thickened dermis with wide collagen bundles separated by gaps that correspond to mucopolysaccharide deposits, visualized using special staining. Several treatments are reported in the literature without well-established results. We report a case of SB in a patient with type 2 diabetes mellitus.