N6-Methyladenine in Eukaryotic DNA: Tissue Distribution, Early Embryo Development, and Neuronal Toxicity

N6-Methyladenine in Eukaryotic DNA: Tissue Distribution, Early Embryo Development, and Neuronal Toxicity

DNA methylation is one of the most important epigenetic modifications and is closely related with several biological processes such as regulation of gene transcription and the development of non-malignant diseases. The prevailing dogma states that DNA methylation in eukaryotes occurs essentially thr...

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Bibliographic Details
Main Authors: Sara B. Fernandes, Nathalie Grova, Sarah Roth, Radu Corneliu Duca, Lode Godderis, Pauline Guebels, Sophie B. Mériaux, Andrew I. Lumley, Pascaline Bouillaud-Kremarik, Isabelle Ernens, Yvan Devaux, Henri Schroeder, Jonathan D. Turner
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Genetics
Subjects:
DNA methylation
6-methyladenine
embryo development
developmental neurotoxicity
stress
brain
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.657171/full

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