Association between Dyslipidemia and Chronic Rhinosinusitis in a Korean Population
This study aims to assess the relationship between chronic rhinosinusitis (CRS) and dyslipidemia in a Korean population. The population aged 40 years or over was selected from the Korean National Health Insurance Service-National Health Screening Cohort. CRS was defined if patients were treated ≥2 t...
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doaj-5d3973add8ec4eed8229ff2758ad1d832020-12-26T00:01:57ZengMDPI AGDiagnostics2075-44182021-12-0111262610.3390/diagnostics11010026Association between Dyslipidemia and Chronic Rhinosinusitis in a Korean PopulationJee Hye Wee0Chanyang Min1Min Woo Park2Soo Hwan Byun3Hyo-Jeong Lee4Chang Myeon Song5Bumjung Park6Hyo Geun Choi7Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang 14068, KoreaHallym Data Science Laboratory, College of Medicine, Hallym University, Anyang 14068, KoreaDepartment of Otorhinolaryngology-Head & Neck Surgery, Kangdong Sacred Heart Hospital, Seoul 05355, KoreaDepartment of Oral & Maxillofacial Surgery, Dentistry, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang 14068, KoreaDepartment of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang 14068, KoreaDepartment of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, Hanyang University, Seoul 04763, KoreaDepartment of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang 14068, KoreaDepartment of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang 14068, KoreaThis study aims to assess the relationship between chronic rhinosinusitis (CRS) and dyslipidemia in a Korean population. The population aged 40 years or over was selected from the Korean National Health Insurance Service-National Health Screening Cohort. CRS was defined if patients were treated ≥2 times with ICD-10 code (J32) and underwent head and neck computed tomography. Patients with CRS were classified as having nasal polyps (J33) or not. Dyslipidemia was defined if participants with the ICD-10 code (E78) were treated ≥2 times from 2002 to 2015. A total of 6163 patients with CRS were matched with 24,652 controls (1:4 ratio) for sex, age, income, and residence. The adjusted odds ratios (aORs) of a previous dyslipidemia in patients with CRS were analyzed by conditional logistic regression analysis, adjusted for confounding factors. The prevalence of dyslipidemia was significantly higher in participants with CRS (26.1%) than in the controls (20.6%) (<i>p</i> < 0.001). There was a significant positive association between CRS with/without nasal polyps and dyslipidemia (aOR = 1.36, 95%CI = 1.26–1.47, <i>p</i> < 0.001). The association between CRS and dyslipidemia was stronger for CRS without nasal polyps (aOR = 1.42, 95% CI = 1.28–1.57, <i>p</i> < 0.001) than for CRS with nasal polyps (aOR = 1.31, 95% CI = 1.17–1.47, <i>p</i> < 0.001). All age and sex subgroups exhibited consistent results. A personal history of dyslipidemia was associated with risk of CRS regardless of total cholesterol and the use of statins.https://www.mdpi.com/2075-4418/11/1/26sinusitisdyslipidemiasnasal polypsinflammationpopulation surveillance |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jee Hye Wee Chanyang Min Min Woo Park Soo Hwan Byun Hyo-Jeong Lee Chang Myeon Song Bumjung Park Hyo Geun Choi |
spellingShingle |
Jee Hye Wee Chanyang Min Min Woo Park Soo Hwan Byun Hyo-Jeong Lee Chang Myeon Song Bumjung Park Hyo Geun Choi Association between Dyslipidemia and Chronic Rhinosinusitis in a Korean Population Diagnostics sinusitis dyslipidemias nasal polyps inflammation population surveillance |
author_facet |
Jee Hye Wee Chanyang Min Min Woo Park Soo Hwan Byun Hyo-Jeong Lee Chang Myeon Song Bumjung Park Hyo Geun Choi |
author_sort |
Jee Hye Wee |
title |
Association between Dyslipidemia and Chronic Rhinosinusitis in a Korean Population |
title_short |
Association between Dyslipidemia and Chronic Rhinosinusitis in a Korean Population |
title_full |
Association between Dyslipidemia and Chronic Rhinosinusitis in a Korean Population |
title_fullStr |
Association between Dyslipidemia and Chronic Rhinosinusitis in a Korean Population |
title_full_unstemmed |
Association between Dyslipidemia and Chronic Rhinosinusitis in a Korean Population |
title_sort |
association between dyslipidemia and chronic rhinosinusitis in a korean population |
publisher |
MDPI AG |
series |
Diagnostics |
issn |
2075-4418 |
publishDate |
2021-12-01 |
description |
This study aims to assess the relationship between chronic rhinosinusitis (CRS) and dyslipidemia in a Korean population. The population aged 40 years or over was selected from the Korean National Health Insurance Service-National Health Screening Cohort. CRS was defined if patients were treated ≥2 times with ICD-10 code (J32) and underwent head and neck computed tomography. Patients with CRS were classified as having nasal polyps (J33) or not. Dyslipidemia was defined if participants with the ICD-10 code (E78) were treated ≥2 times from 2002 to 2015. A total of 6163 patients with CRS were matched with 24,652 controls (1:4 ratio) for sex, age, income, and residence. The adjusted odds ratios (aORs) of a previous dyslipidemia in patients with CRS were analyzed by conditional logistic regression analysis, adjusted for confounding factors. The prevalence of dyslipidemia was significantly higher in participants with CRS (26.1%) than in the controls (20.6%) (<i>p</i> < 0.001). There was a significant positive association between CRS with/without nasal polyps and dyslipidemia (aOR = 1.36, 95%CI = 1.26–1.47, <i>p</i> < 0.001). The association between CRS and dyslipidemia was stronger for CRS without nasal polyps (aOR = 1.42, 95% CI = 1.28–1.57, <i>p</i> < 0.001) than for CRS with nasal polyps (aOR = 1.31, 95% CI = 1.17–1.47, <i>p</i> < 0.001). All age and sex subgroups exhibited consistent results. A personal history of dyslipidemia was associated with risk of CRS regardless of total cholesterol and the use of statins. |
topic |
sinusitis dyslipidemias nasal polyps inflammation population surveillance |
url |
https://www.mdpi.com/2075-4418/11/1/26 |
work_keys_str_mv |
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