Mucosal immunization with integrase-defective lentiviral vectors protects against influenza virus challenge in mice.
Recent reports highlight the potential for integrase-defective lentiviral vectors (IDLV) to be developed as vaccines due to their ability to elicit cell-mediated and humoral immune responses after intramuscular administration. Differently from their integrase-competent counterpart, whose utility for...
Main Authors: | Judith M Fontana, Paul J Christos, Zuleika Michelini, Donatella Negri, Andrea Cara, Mirella Salvatore |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4019533?pdf=render |
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