A dual-target molecular mechanism of pyrethrum repellency against mosquitoes

A dual-target molecular mechanism of pyrethrum repellency against mosquitoes

Although pyrethrum is used to repel insects for centuries, the underlying mechanism has been enigmatic. Liu et al. found that specific components of pyrethrum mediate repellency by targeting olfactory receptors and/or voltage-gated sodium channels in Aedes aegypti mosquitoes.

Bibliographic Details
Main Authors: Feng Liu, Qiang Wang, Peng Xu, Felipe Andreazza, Wilson R. Valbon, Elizabeth Bandason, Mengli Chen, Ru Yan, Bo Feng, Leticia B. Smith, Jeffrey G. Scott, Genki Takamatsu, Makoto Ihara, Kazuhiko Matsuda, James Klimavicz, Joel Coats, Eugenio E. Oliveira, Yuzhe Du, Ke Dong
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22847-0
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spelling doaj-5d3f109d9e214b4ba1f8ec0e86376c4a2021-05-09T11:13:04ZengNature Publishing GroupNature Communications2041-17232021-05-011211910.1038/s41467-021-22847-0A dual-target molecular mechanism of pyrethrum repellency against mosquitoesFeng Liu0Qiang Wang1Peng Xu2Felipe Andreazza3Wilson R. Valbon4Elizabeth Bandason5Mengli Chen6Ru Yan7Bo Feng8Leticia B. Smith9Jeffrey G. Scott10Genki Takamatsu11Makoto Ihara12Kazuhiko Matsuda13James Klimavicz14Joel Coats15Eugenio E. Oliveira16Yuzhe Du17Ke Dong18Department of Entomology, Michigan State UniversityDepartment of Entomology, Michigan State UniversityDepartment of Entomology, Michigan State UniversityDepartment of Entomology, Michigan State UniversityDepartment of Entomology, Michigan State UniversityDepartment of Entomology, Michigan State UniversityInstitute of Pesticide and Environmental Toxicology, Zhejiang UniversityInstitute of Pesticide and Environmental Toxicology, Zhejiang UniversityDepartment of Entomology, Michigan State UniversityDepartment of Entomology, Cornell UniversityDepartment of Entomology, Cornell UniversityDepartment of Applied Biological Chemistry, Faculty of Agriculture, Kindai UniversityDepartment of Applied Biological Chemistry, Faculty of Agriculture, Kindai UniversityDepartment of Applied Biological Chemistry, Faculty of Agriculture, Kindai UniversityDepartment of Entomology, Iowa State UniversityDepartment of Entomology, Iowa State UniversityDepartment of Entomology, Michigan State UniversityDepartment of Entomology, Michigan State UniversityDepartment of Entomology, Michigan State UniversityAlthough pyrethrum is used to repel insects for centuries, the underlying mechanism has been enigmatic. Liu et al. found that specific components of pyrethrum mediate repellency by targeting olfactory receptors and/or voltage-gated sodium channels in Aedes aegypti mosquitoes.https://doi.org/10.1038/s41467-021-22847-0
collection DOAJ
language English
format Article
sources DOAJ
author Feng Liu
Qiang Wang
Peng Xu
Felipe Andreazza
Wilson R. Valbon
Elizabeth Bandason
Mengli Chen
Ru Yan
Bo Feng
Leticia B. Smith
Jeffrey G. Scott
Genki Takamatsu
Makoto Ihara
Kazuhiko Matsuda
James Klimavicz
Joel Coats
Eugenio E. Oliveira
Yuzhe Du
Ke Dong
spellingShingle Feng Liu
Qiang Wang
Peng Xu
Felipe Andreazza
Wilson R. Valbon
Elizabeth Bandason
Mengli Chen
Ru Yan
Bo Feng
Leticia B. Smith
Jeffrey G. Scott
Genki Takamatsu
Makoto Ihara
Kazuhiko Matsuda
James Klimavicz
Joel Coats
Eugenio E. Oliveira
Yuzhe Du
Ke Dong
A dual-target molecular mechanism of pyrethrum repellency against mosquitoes
Nature Communications
author_facet Feng Liu
Qiang Wang
Peng Xu
Felipe Andreazza
Wilson R. Valbon
Elizabeth Bandason
Mengli Chen
Ru Yan
Bo Feng
Leticia B. Smith
Jeffrey G. Scott
Genki Takamatsu
Makoto Ihara
Kazuhiko Matsuda
James Klimavicz
Joel Coats
Eugenio E. Oliveira
Yuzhe Du
Ke Dong
author_sort Feng Liu
title A dual-target molecular mechanism of pyrethrum repellency against mosquitoes
title_short A dual-target molecular mechanism of pyrethrum repellency against mosquitoes
title_full A dual-target molecular mechanism of pyrethrum repellency against mosquitoes
title_fullStr A dual-target molecular mechanism of pyrethrum repellency against mosquitoes
title_full_unstemmed A dual-target molecular mechanism of pyrethrum repellency against mosquitoes
title_sort dual-target molecular mechanism of pyrethrum repellency against mosquitoes
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-05-01
description Although pyrethrum is used to repel insects for centuries, the underlying mechanism has been enigmatic. Liu et al. found that specific components of pyrethrum mediate repellency by targeting olfactory receptors and/or voltage-gated sodium channels in Aedes aegypti mosquitoes.
url https://doi.org/10.1038/s41467-021-22847-0
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