Immunochemical evidence that human apoB differs when expressed in rodent versus human cells

Immunochemical evidence that human apoB differs when expressed in rodent versus human cells

LDL from human apolipoprotein B-100 (apoB-100) transgenic (HuBTg+/+) mice contains more triglyceride than LDL from normolipidemic subjects. To obtain novel monoclonal antibody (MAb) probes of apoB conformation, we generated hybridomas from HuBTg+/+ that had been immunized with LDL isolated from huma...

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Bibliographic Details
Main Authors: Xingyu Wang, Vinita Chauhan, Anh T. Nguyen, Joshua Schultz, Jean Davignon, Stephen G. Young, Jan Borén, Thomas L. Innerarity, Hui Rutai, Ross W. Milne
Format: Article
Language:English
Published: Elsevier 2003-03-01
Series:Journal of Lipid Research
Subjects:
low density lipoproteins
apolipoprotein B
hybridoma
polymorphism
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520311949

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