Compensation of brain shift during surgery using non-rigid registration of MR and ultrasound images
Background: Surgery and accurate removal of the brain tumor in the operating room and after opening the scalp is one of the major challenges for neurosurgeons due to the removal of skull pressure and displacement and deformation of the brain tissue. This displacement of the brain changes the locatio...
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Tehran University of Medical Sciences
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doaj-5d40243813da488ab00aa031dfe16b002021-02-09T05:28:57ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222020-12-017810658667Compensation of brain shift during surgery using non-rigid registration of MR and ultrasound imagesAmir Hossein Jalalzadeh0Ahmad Shalbaf1Arash Maghsoudi2 Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran. Department of Biomedical Engineering and Medical Physics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran. Background: Surgery and accurate removal of the brain tumor in the operating room and after opening the scalp is one of the major challenges for neurosurgeons due to the removal of skull pressure and displacement and deformation of the brain tissue. This displacement of the brain changes the location of the tumor relative to the MR image taken preoperatively. Methods: This study, which is done from March to December 2019 in Tehran, is evaluated on the available database of RetroSpective Evaluation of Cerebral Tumors (RESECT) including pre-operative MR images, and intra-operative ultrasound from 22 patients with low-grade gliomas who underwent surgeries at St. Olavs University Hospital. This study is used for image registration of preoperative MR imaging and ultrasound imaging after resection of the skull to compensate for brain changes. By this method, we obtained a third image that resembles preoperative MR imaging but has the geometry of the brain shape changes. We used a combination of the two transformations named Affine and non-rigid Free Form Deformation (FFD) for hierarchically moving the pixels to compensate for global variations, and also nonlinear local and small variations. Also, by applying the mutual information function, we consider the entropy value as the criterion of similarity due to the non-similarity of the nature of the images. Also, Limited Broyden-Fletcher-Goldfarb-Shannon method is used for optimization. Results: The results of the proposed method were presented on the available database of RetroSpective Evaluation of Cerebral Tumors (RESECT) including images of 22 patients with glioma type 2 tumors and evaluated based on 15 landmarks per patient and also mutual information criteria. The mean target registration error for affine, FFD and the proposed method are 46.19, 42.85 and 38.01, respectively. It was shown that the proposed method achieved high accuracy by combining the two transformations of affine and FFD compared to the separate use of each of the two models. Conclusion: In image registration of preoperative MR and ultrasound images for compensation of brain shift, the combination of affine and FFD transformations had better results than the individual use of each of the transformations.http://tumj.tums.ac.ir/article-1-10930-en.htmlbrainimage processingmagnetic resonance imagingultrasonography. |
collection |
DOAJ |
language |
fas |
format |
Article |
sources |
DOAJ |
author |
Amir Hossein Jalalzadeh Ahmad Shalbaf Arash Maghsoudi |
spellingShingle |
Amir Hossein Jalalzadeh Ahmad Shalbaf Arash Maghsoudi Compensation of brain shift during surgery using non-rigid registration of MR and ultrasound images Tehran University Medical Journal brain image processing magnetic resonance imaging ultrasonography. |
author_facet |
Amir Hossein Jalalzadeh Ahmad Shalbaf Arash Maghsoudi |
author_sort |
Amir Hossein Jalalzadeh |
title |
Compensation of brain shift during surgery using non-rigid
registration of MR and ultrasound images |
title_short |
Compensation of brain shift during surgery using non-rigid
registration of MR and ultrasound images |
title_full |
Compensation of brain shift during surgery using non-rigid
registration of MR and ultrasound images |
title_fullStr |
Compensation of brain shift during surgery using non-rigid
registration of MR and ultrasound images |
title_full_unstemmed |
Compensation of brain shift during surgery using non-rigid
registration of MR and ultrasound images |
title_sort |
compensation of brain shift during surgery using non-rigid
registration of mr and ultrasound images |
publisher |
Tehran University of Medical Sciences |
series |
Tehran University Medical Journal |
issn |
1683-1764 1735-7322 |
publishDate |
2020-12-01 |
description |
Background: Surgery and accurate removal of the brain tumor in the operating room and after opening the scalp is one of the major challenges for neurosurgeons due to the removal of skull pressure and displacement and deformation of the brain tissue. This displacement of the brain changes the location of the tumor relative to the MR image taken preoperatively.
Methods: This study, which is done from March to December 2019 in Tehran, is evaluated on the available database of RetroSpective Evaluation of Cerebral Tumors (RESECT) including pre-operative MR images, and intra-operative ultrasound from 22 patients with low-grade gliomas who underwent surgeries at St. Olavs University Hospital. This study is used for image registration of preoperative MR imaging and ultrasound imaging after resection of the skull to compensate for brain changes. By this method, we obtained a third image that resembles preoperative MR imaging but has the geometry of the brain shape changes. We used a combination of the two transformations named Affine and non-rigid Free Form Deformation (FFD) for hierarchically moving the pixels to compensate for global variations, and also nonlinear local and small variations. Also, by applying the mutual information function, we consider the entropy value as the criterion of similarity due to the non-similarity of the nature of the images. Also, Limited Broyden-Fletcher-Goldfarb-Shannon method is used for optimization.
Results: The results of the proposed method were presented on the available database of RetroSpective Evaluation of Cerebral Tumors (RESECT) including images of 22 patients with glioma type 2 tumors and evaluated based on 15 landmarks per patient and also mutual information criteria. The mean target registration error for affine, FFD and the proposed method are 46.19, 42.85 and 38.01, respectively. It was shown that the proposed method achieved high accuracy by combining the two transformations of affine and FFD compared to the separate use of each of the two models.
Conclusion: In image registration of preoperative MR and ultrasound images for compensation of brain shift, the combination of affine and FFD transformations had better results than the individual use of each of the transformations. |
topic |
brain image processing magnetic resonance imaging ultrasonography. |
url |
http://tumj.tums.ac.ir/article-1-10930-en.html |
work_keys_str_mv |
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