Correlation between parasitemia and spleen size in patients with P. falciparum infection
Background Spleen is an important organ in immunity to malaria infection which is always affected in malaria patients. Enlargement of the spleen is one of the main clinical symptoms of malaria. Level of parasitemia is related to the risk of complications. Objective To describe the correlation betwee...
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doaj-5d5090b59ef248989cb38cb97a7979912020-11-25T01:29:35ZengIndonesian Pediatric Society Publishing HousePaediatrica Indonesiana0030-93112338-476X2016-10-01443111610.14238/pi44.3.2004.111-6613Correlation between parasitemia and spleen size in patients with P. falciparum infectionDini LailaniMunar LubisBidasari LubisSyahril PasaribuBackground Spleen is an important organ in immunity to malaria infection which is always affected in malaria patients. Enlargement of the spleen is one of the main clinical symptoms of malaria. Level of parasitemia is related to the risk of complications. Objective To describe the correlation between parasitemia and spleen size in patients with P.falciparum infection. Methods One hundred and four patients including children and adults with fever, pale, jaundice, diarrhea, and headache who vis- ited public health centers in 5 villages in Mandailing Natal, North Sumatera were enrolled in this study. The diagnosis of malaria was based on blood smears stained by Giemsa method, while the spleen size was measured using Hackett method. Correlation be- tween parasitemia and spleen size was tested by Spearman rank correlation. Results Splenomegaly was found in 37 of 104 patients (35.6 %) with the size of H1 in 10.6 %, H2 in 15.4 %, H3 in 9.6 %. The mean parasite count between patients with and without splenomegaly was different, and the difference was significant between patients with spleen size of H0 and H3. The higher the parasitemia, the bigger the spleen size was (r=0.291; p=0.03). Conclusion There was a correlation between parasitemia and spleen size in falciparum malarial infectionhttps://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/747parasitemiasplenomegalyfalciparum malaria |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dini Lailani Munar Lubis Bidasari Lubis Syahril Pasaribu |
spellingShingle |
Dini Lailani Munar Lubis Bidasari Lubis Syahril Pasaribu Correlation between parasitemia and spleen size in patients with P. falciparum infection Paediatrica Indonesiana parasitemia splenomegaly falciparum malaria |
author_facet |
Dini Lailani Munar Lubis Bidasari Lubis Syahril Pasaribu |
author_sort |
Dini Lailani |
title |
Correlation between parasitemia and spleen size in patients with P. falciparum infection |
title_short |
Correlation between parasitemia and spleen size in patients with P. falciparum infection |
title_full |
Correlation between parasitemia and spleen size in patients with P. falciparum infection |
title_fullStr |
Correlation between parasitemia and spleen size in patients with P. falciparum infection |
title_full_unstemmed |
Correlation between parasitemia and spleen size in patients with P. falciparum infection |
title_sort |
correlation between parasitemia and spleen size in patients with p. falciparum infection |
publisher |
Indonesian Pediatric Society Publishing House |
series |
Paediatrica Indonesiana |
issn |
0030-9311 2338-476X |
publishDate |
2016-10-01 |
description |
Background Spleen is an important organ in immunity to malaria
infection which is always affected in malaria patients. Enlargement
of the spleen is one of the main clinical symptoms of malaria. Level
of parasitemia is related to the risk of complications.
Objective To describe the correlation between parasitemia and
spleen size in patients with P.falciparum infection.
Methods One hundred and four patients including children and
adults with fever, pale, jaundice, diarrhea, and headache who vis-
ited public health centers in 5 villages in Mandailing Natal, North
Sumatera were enrolled in this study. The diagnosis of malaria
was based on blood smears stained by Giemsa method, while the
spleen size was measured using Hackett method. Correlation be-
tween parasitemia and spleen size was tested by Spearman rank
correlation.
Results Splenomegaly was found in 37 of 104 patients (35.6 %)
with the size of H1 in 10.6 %, H2 in 15.4 %, H3 in 9.6 %. The mean
parasite count between patients with and without splenomegaly
was different, and the difference was significant between patients
with spleen size of H0 and H3. The higher the parasitemia, the
bigger the spleen size was (r=0.291; p=0.03).
Conclusion There was a correlation between parasitemia and
spleen size in falciparum malarial infection |
topic |
parasitemia splenomegaly falciparum malaria |
url |
https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/747 |
work_keys_str_mv |
AT dinilailani correlationbetweenparasitemiaandspleensizeinpatientswithpfalciparuminfection AT munarlubis correlationbetweenparasitemiaandspleensizeinpatientswithpfalciparuminfection AT bidasarilubis correlationbetweenparasitemiaandspleensizeinpatientswithpfalciparuminfection AT syahrilpasaribu correlationbetweenparasitemiaandspleensizeinpatientswithpfalciparuminfection |
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