INTRA-UTERINE GROWTH RETARDATION AND DEVELOPMENT OF HYPERTENSION
Low birth weight (LBW) is defined as a birth weight of a liveborn infant of <2,500 gram. In developed countries, LBW is commonly caused by preterm birth; while in developing countries, it is mostly due to intrauterine growth retardation. The concept of developmental origins of adult diseases, par...
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doaj-5d527384e1e8488c88a6e9e07fb6aa0d2020-11-24T23:41:45ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322017-02-01484320324179INTRA-UTERINE GROWTH RETARDATION AND DEVELOPMENT OF HYPERTENSIONHaerani Rasyid0Syakib Bakri1Department of Internal Medicine, Faculty of Medicine, Hasanuddin University - Dr. Wahidin Sudirohusodo Hospital, Makassar, South Sulawesi, IndonesiaDepartment of Internal Medicine, Faculty of Medicine, Hasanuddin University - Dr. Wahidin Sudirohusodo Hospital, Makassar, South Sulawesi, IndonesiaLow birth weight (LBW) is defined as a birth weight of a liveborn infant of <2,500 gram. In developed countries, LBW is commonly caused by preterm birth; while in developing countries, it is mostly due to intrauterine growth retardation. The concept of developmental origins of adult diseases, particularly on late-onset diseases such as hypertension and kidney disease, implies that there is a correlation between intrauterine milieu, intrauterine growth retardation, premature birth and infant feeding. The ‘fetal origin hypothesis’ suggests that metabolic diseases are directly related to poor nutritional status in early life. There is an inverse association between LBW and later risk of hypertension. The pathomechanism that links LBW and hypertension is multifactorial including delayed nephrogenesis, genetic factors, sympathetic hyperactivity, endothel dysfunction, elastin deficiencies, insulin resistance and activation of renin-angiotension system.http://www.actamedindones.org/index.php/ijim/article/view/263Intra-uterine growth retardationHypertension |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Haerani Rasyid Syakib Bakri |
spellingShingle |
Haerani Rasyid Syakib Bakri INTRA-UTERINE GROWTH RETARDATION AND DEVELOPMENT OF HYPERTENSION Acta Medica Indonesiana Intra-uterine growth retardation Hypertension |
author_facet |
Haerani Rasyid Syakib Bakri |
author_sort |
Haerani Rasyid |
title |
INTRA-UTERINE GROWTH RETARDATION AND DEVELOPMENT OF HYPERTENSION |
title_short |
INTRA-UTERINE GROWTH RETARDATION AND DEVELOPMENT OF HYPERTENSION |
title_full |
INTRA-UTERINE GROWTH RETARDATION AND DEVELOPMENT OF HYPERTENSION |
title_fullStr |
INTRA-UTERINE GROWTH RETARDATION AND DEVELOPMENT OF HYPERTENSION |
title_full_unstemmed |
INTRA-UTERINE GROWTH RETARDATION AND DEVELOPMENT OF HYPERTENSION |
title_sort |
intra-uterine growth retardation and development of hypertension |
publisher |
Interna Publishing |
series |
Acta Medica Indonesiana |
issn |
0125-9326 2338-2732 |
publishDate |
2017-02-01 |
description |
Low birth weight (LBW) is defined as a birth weight of a liveborn infant of <2,500 gram. In developed countries, LBW is commonly caused by preterm birth; while in developing countries, it is mostly due to intrauterine growth retardation. The concept of developmental origins of adult diseases, particularly on late-onset diseases such as hypertension and kidney disease, implies that there is a correlation between intrauterine milieu, intrauterine growth retardation, premature birth and infant feeding. The ‘fetal origin hypothesis’ suggests that metabolic diseases are directly related to poor nutritional status in early life.
There is an inverse association between LBW and later risk of hypertension. The pathomechanism that links LBW and hypertension is multifactorial including delayed nephrogenesis, genetic factors, sympathetic hyperactivity, endothel dysfunction, elastin deficiencies, insulin resistance and activation of renin-angiotension system. |
topic |
Intra-uterine growth retardation Hypertension |
url |
http://www.actamedindones.org/index.php/ijim/article/view/263 |
work_keys_str_mv |
AT haeranirasyid intrauterinegrowthretardationanddevelopmentofhypertension AT syakibbakri intrauterinegrowthretardationanddevelopmentofhypertension |
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1725505497164939264 |