Antitumor Macrophage Response to Bacillus pumilus Ribonuclease (Binase)

Extracellular bacterial ribonucleases such as binase from Bacillus pumilus possess cytotoxic activity against tumor cells with a potential for clinical application. Moreover, they may induce activation of tumor-derived macrophages either into the M1-phenotype with well-documented functions in the re...

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Bibliographic Details
Main Authors: Anna Makeeva, Hector A. Cabrera-Fuentes, Julian Rodriguez-Montesinos, Pavel Zelenikhin, Alexander Nesmelov, Klaus T. Preissner, Olga N. Ilinskaya
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2017/4029641