The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults.
BACKGROUND: The prevalence of type 2 diabetes within the Republic of Ireland is poorly defined, although a recent report suggested 135,000 cases in adults aged 45+, with approximately one-third of these undiagnosed. This study aims to assess the prevalence of undiagnosed and diagnosed diabetes in mi...
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doaj-5d58d5bf1aca49ac9a514836d832476e2020-11-25T02:22:53ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-01811e8050410.1371/journal.pone.0080504The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults.Jennifer M O ConnorSeán R MillarClaire M BuckleyPatricia M KearneyIvan J PerryBACKGROUND: The prevalence of type 2 diabetes within the Republic of Ireland is poorly defined, although a recent report suggested 135,000 cases in adults aged 45+, with approximately one-third of these undiagnosed. This study aims to assess the prevalence of undiagnosed and diagnosed diabetes in middle-aged adults, and compare features related to either condition, in order to investigate why certain individuals remain undetected. METHODS: This was a cross-sectional study involving a sample of 2,047 men and women, aged between 50-69 years, randomly selected from a large primary care centre. Univariate logistic regression was used to explore socio-economic, metabolic and other health related variable associations with undiagnosed or diagnosed diabetes. A final multivariate analysis was used to determine odds ratios and 95% confidence intervals for having undiagnosed compared to diagnosed diabetes, adjusted for gender, age and significant covariates determined from univariate models. PRINCIPLE FINDINGS: The total prevalence of diabetes was 8.5% (95% CI: 7.4%-8.8%); 72 subjects (3.5%) had undiagnosed diabetes (95% CI: 2.8%-4.4%) and 102 subjects (5.0%) had diagnosed diabetes (95% CI: 4.1%-6.0%). Obesity, dyslipidaemia, and family history of diabetes were positively associated with both undiagnosed and diagnosed type 2 diabetes. Compared with diagnosed subjects, study participants with undiagnosed diabetes were significantly more likely to have low levels of physical activity and were less likely to be on treatment for diabetes-related conditions or to have private medical insurance. CONCLUSIONS: The prevalence of diabetes within the Cork and Kerry Diabetes and Heart Disease Study is comparable to recent estimates from the Slán National Health and Lifestyle Survey, a study which was nationally representative of the general population. A considerable proportion of diabetes cases were undiagnosed (41%), emphasising the need for more effective detection strategies and equitable access to primary healthcare.http://europepmc.org/articles/PMC3840064?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jennifer M O Connor Seán R Millar Claire M Buckley Patricia M Kearney Ivan J Perry |
spellingShingle |
Jennifer M O Connor Seán R Millar Claire M Buckley Patricia M Kearney Ivan J Perry The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults. PLoS ONE |
author_facet |
Jennifer M O Connor Seán R Millar Claire M Buckley Patricia M Kearney Ivan J Perry |
author_sort |
Jennifer M O Connor |
title |
The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults. |
title_short |
The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults. |
title_full |
The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults. |
title_fullStr |
The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults. |
title_full_unstemmed |
The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults. |
title_sort |
prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2013-01-01 |
description |
BACKGROUND: The prevalence of type 2 diabetes within the Republic of Ireland is poorly defined, although a recent report suggested 135,000 cases in adults aged 45+, with approximately one-third of these undiagnosed. This study aims to assess the prevalence of undiagnosed and diagnosed diabetes in middle-aged adults, and compare features related to either condition, in order to investigate why certain individuals remain undetected. METHODS: This was a cross-sectional study involving a sample of 2,047 men and women, aged between 50-69 years, randomly selected from a large primary care centre. Univariate logistic regression was used to explore socio-economic, metabolic and other health related variable associations with undiagnosed or diagnosed diabetes. A final multivariate analysis was used to determine odds ratios and 95% confidence intervals for having undiagnosed compared to diagnosed diabetes, adjusted for gender, age and significant covariates determined from univariate models. PRINCIPLE FINDINGS: The total prevalence of diabetes was 8.5% (95% CI: 7.4%-8.8%); 72 subjects (3.5%) had undiagnosed diabetes (95% CI: 2.8%-4.4%) and 102 subjects (5.0%) had diagnosed diabetes (95% CI: 4.1%-6.0%). Obesity, dyslipidaemia, and family history of diabetes were positively associated with both undiagnosed and diagnosed type 2 diabetes. Compared with diagnosed subjects, study participants with undiagnosed diabetes were significantly more likely to have low levels of physical activity and were less likely to be on treatment for diabetes-related conditions or to have private medical insurance. CONCLUSIONS: The prevalence of diabetes within the Cork and Kerry Diabetes and Heart Disease Study is comparable to recent estimates from the Slán National Health and Lifestyle Survey, a study which was nationally representative of the general population. A considerable proportion of diabetes cases were undiagnosed (41%), emphasising the need for more effective detection strategies and equitable access to primary healthcare. |
url |
http://europepmc.org/articles/PMC3840064?pdf=render |
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