Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures
Abstract Background Advances in next-generation sequencing (NGS) of antibody repertoires have led to an explosion in B cell receptor sequence data from donors with many different disease states. These data have the potential to detect patterns of immune response across populations. However, to this...
Main Authors: | Alexander M. Sevy, Cinque Soto, Robin G. Bombardi, Jens Meiler, James E. Crowe |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-019-3281-8 |
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