A critical role for mTORC1 in erythropoiesis and anemia
Red blood cells (RBC) must coordinate their rate of growth and proliferation with the availability of nutrients, such as iron, but the signaling mechanisms that link the nutritional state to RBC growth are incompletely understood. We performed a screen for cell types that have high levels of signali...
Main Authors: | Zachary A Knight, Sarah F Schmidt, Kivanc Birsoy, Keith Tan, Jeffrey M Friedman |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/01913 |
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