MATHEMATICAL MODELING AS A MODERN TOOL OF PROJECTING THE EFFICACY OF ROTAVIRUS VACCINES

MATHEMATICAL MODELING AS A MODERN TOOL OF PROJECTING THE EFFICACY OF ROTAVIRUS VACCINES

With the use of molecular biological studies there were estimated the peculiarities of the circulation of rotavirus genotypes on the territory of Ukraine. It was estimated predictive genotype-specific efficacy of the vaccine based on rotavirus strain RIX4114 with genotype G1P, based on the methods o...

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Main Author: S. O. Solovyov
Format: Article
Language:English
Published: Ukrmedknyha Publishing House 2012-11-01
Series:Medična Informatika ta Inženerìâ
Online Access:http://ojs.tdmu.edu.ua/index.php/here/article/view/43
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spelling doaj-5d86b32269cb45e0ac68a62e44bf69922020-11-25T00:08:59ZengUkrmedknyha Publishing HouseMedična Informatika ta Inženerìâ1996-19601997-74682012-11-010210.11603/mie.1996-1960.2011.2.4341MATHEMATICAL MODELING AS A MODERN TOOL OF PROJECTING THE EFFICACY OF ROTAVIRUS VACCINESS. O. Solovyov0Національна медична академія післядипломної освіти імені П. Л. ШупикаWith the use of molecular biological studies there were estimated the peculiarities of the circulation of rotavirus genotypes on the territory of Ukraine. It was estimated predictive genotype-specific efficacy of the vaccine based on rotavirus strain RIX4114 with genotype G1P, based on the methods of distribution and multiplicative synthesis, which were used for the first time in such calculations. This allows obtaining a preliminary evaluation of its efficacy prior to clinical trials. It was established that the calculated value is sufficiently high (80,4%) in conditions of its mass use among population of Ukraine.http://ojs.tdmu.edu.ua/index.php/here/article/view/43
collection DOAJ
language English
format Article
sources DOAJ
author S. O. Solovyov
spellingShingle S. O. Solovyov
MATHEMATICAL MODELING AS A MODERN TOOL OF PROJECTING THE EFFICACY OF ROTAVIRUS VACCINES
Medična Informatika ta Inženerìâ
author_facet S. O. Solovyov
author_sort S. O. Solovyov
title MATHEMATICAL MODELING AS A MODERN TOOL OF PROJECTING THE EFFICACY OF ROTAVIRUS VACCINES
title_short MATHEMATICAL MODELING AS A MODERN TOOL OF PROJECTING THE EFFICACY OF ROTAVIRUS VACCINES
title_full MATHEMATICAL MODELING AS A MODERN TOOL OF PROJECTING THE EFFICACY OF ROTAVIRUS VACCINES
title_fullStr MATHEMATICAL MODELING AS A MODERN TOOL OF PROJECTING THE EFFICACY OF ROTAVIRUS VACCINES
title_full_unstemmed MATHEMATICAL MODELING AS A MODERN TOOL OF PROJECTING THE EFFICACY OF ROTAVIRUS VACCINES
title_sort mathematical modeling as a modern tool of projecting the efficacy of rotavirus vaccines
publisher Ukrmedknyha Publishing House
series Medična Informatika ta Inženerìâ
issn 1996-1960
1997-7468
publishDate 2012-11-01
description With the use of molecular biological studies there were estimated the peculiarities of the circulation of rotavirus genotypes on the territory of Ukraine. It was estimated predictive genotype-specific efficacy of the vaccine based on rotavirus strain RIX4114 with genotype G1P, based on the methods of distribution and multiplicative synthesis, which were used for the first time in such calculations. This allows obtaining a preliminary evaluation of its efficacy prior to clinical trials. It was established that the calculated value is sufficiently high (80,4%) in conditions of its mass use among population of Ukraine.
url http://ojs.tdmu.edu.ua/index.php/here/article/view/43
work_keys_str_mv AT sosolovyov mathematicalmodelingasamoderntoolofprojectingtheefficacyofrotavirusvaccines
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