Gold nanoparticles: Synthesis properties and applications

• Main Authors: Inès Hammami, Nadiyah M. Alabdallah, Amjad Al jomaa, Madiha kamoun
• Format: Article
• Language: English
• Published: Elsevier 2021-10-01
• Series: Journal of King Saud University: Science
• Subjects: Nanoparticles; Gold nanoparticles; AuNPs; Anticancer activities
• Online Access: http://www.sciencedirect.com/science/article/pii/S1018364721002214

In recent years, nanotechnology has been the topic of extensive research and a great deal of interest among researchers. The manufacturing and utilization of nanoparticles (NPs) has expanded dramatically as a result of the rapid development of nanotechnology. Gold nanoparticles (AuNPs) are one of the most important nanoparticles, and they have been widely used for medical and non-medical applications as ideal material because of their unique distinct features: inert, biocompatible, and especially due to low toxicity. It is can be manufacture on a massive scale by reducing the oxidation of gold Au+1(aureus) or Au+3(auric) to Au0 by subjoin a reducing agent through various physical, chemical, and biological methods under different circumstance. Researchers have been motivated by the harmful effects of current synthesis methods to focus on the production of environmentally sustainable and green synthesis using non-toxic chemicals from natural sources, such as plant extract, bacteria, and fungi. The preparation of Gold nanoparticles can be done inwardly or outside by microbes, but outside the cell handling is facile in terms of insulation. Modified nanocellulose is a preferred technique for gold nanoparticle extraction. AuNPs have shown outstanding applications for diagnostic and therapeutic uses, including biosensor applications, tumor-targeting capability (Anticancer Activity) for cancer therapy, and precise drug delivery of nano-vehicles to diseased tissues.