The Effects of Maternal Separation on Adult Methamphetamine Self-Administration, Extinction, Reinstatement, and MeCP2 Immunoreactivity in the Nucleus Accumbens

The Effects of Maternal Separation on Adult Methamphetamine Self-Administration, Extinction, Reinstatement, and MeCP2 Immunoreactivity in the Nucleus Accumbens

The maternal separation (MS) paradigm is an animal model of early life stress. Animals subjected to MS during the first two weeks of life display altered behavioral and neuroendocrinological stress responses as adults. MS also produces altered responsiveness to and self-administration (SA) of variou...

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Bibliographic Details
Main Authors: Candace R. Lewis, Kelsey eStaudinger, Lena eScheck, M Foster eOlive
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Psychiatry
Subjects:
Methamphetamine
Nucleus Accumbens
MeCP2
maternal separation
self-administration
early life stress
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00055/full

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