The method of hermetic sealing of iatrogenic damage of fetal membranes during fetal surgical interventions

• Main Authors: M.G.Shneyderman, T.Kh.Fatkhudinov, N.K.Tetruashvili, K.V.Kostyukov, V.A.Sakalo, I.V.Arutyunyan, K.A.Gladkova, R.G.Shmakov
• Format: Article
• Language: Russian
• Published: IP Berlin A.V. 2018-01-01
• Series: Гинекология
• Subjects: fetoscopy; fetal surgery; diaphragmatic hernia; feto-fetal transfusion syndrome; premature rupture of membranes; tissue sealant; plasma enriched with platelets; amniotic catheter
• Online Access: http://gynecology.orscience.ru/en/archive/2018/vol-20-1-2018/17_2843/?element

The article presents a new method for treating iatrogenic damage to membranes in fetuscopic interventions. Since surgical treatment during pregnancy is associated with the use of trocar and amniotic fetal puncture, the most frequent complication of this procedure is premature discharge of amniotic fluid and abortion (28–67%). The new method of treatment is based on the use of the technique of safe and effective hermetic sealing of fetal membranes in fetoscopy, which will reduce the frequency of iatrogenic complications. The Ministry of Health of the Russian Federation has developed a method and created the main components for hermetic sealing of membranes: a tissue sealant from the blood components of the mother – a plasma enriched with platelets, which can be injected into the area of the defect of the fetal bladder in the form of a gel and an amniotic catheter providing effective sealing of the trocar hole from the inner and outer surfaces of the membranes. We described the results of a laboratory experiment on animals, discussed the effectiveness of a new method of treatment and the possibility of its practical application.